(S)-(-)-Ketamine
Brand names,
(S)-(-)-Ketamine
Analogs
(S)-(-)-Ketamine
Brand Names Mixture
(S)-(-)-Ketamine
Chemical_Formula
C13H16ClNO
(S)-(-)-Ketamine
RX_link
http://www.rxlist.com/cgi/generic3/ketamine.htm
(S)-(-)-Ketamine
fda sheet
(S)-(-)-Ketamine
msds (material safety sheet)
(S)-(-)-Ketamine
Synthesis Reference
No information avaliable
(S)-(-)-Ketamine
Molecular Weight
237.725 g/mol
(S)-(-)-Ketamine
Melting Point
92.5 oC
(S)-(-)-Ketamine
H2O Solubility
No information avaliable
(S)-(-)-Ketamine
State
Solid
(S)-(-)-Ketamine
LogP
3.032
(S)-(-)-Ketamine
Dosage Forms
Solution
(S)-(-)-Ketamine
Indication
For use as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation.
(S)-(-)-Ketamine
Pharmacology
Ketamine is a rapid-acting general anesthetic producing an anesthetic state characterized by profound analgesia, normal pharyngeal-laryngeal reflexes, normal or slightly enhanced skeletal muscle tone, cardiovascular and respiratory stimulation, and occasionally a transient and minimal respiratory depression. Ketamine is indicated as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. The anesthetic state produced by Ketamine has been termed “dissociative anesthesia” in that it appears to selectively interrupt association pathways of the brain before producing somesthetic sensory blockade. It may selectively depress the thalamoneocortical system before significantly obtunding the more ancient cerebral centers and pathways (reticularactivating and limbic systems).
(S)-(-)-Ketamine
Absorption
Rapidly absorbed following parenteral administration.
(S)-(-)-Ketamine
side effects and Toxicity
No information avaliable
(S)-(-)-Ketamine
Patient Information
PATIENT INFORMATION
Follow the links
http://www.rxlist.com/cgi/generic3/ketamine_pi.htm
http://www.rxlist.com/cgi/generic3/ketamine_wcp.htm
http://www.drugs.com/cons/Ketamine.html
(S)-(-)-Ketamine
Organisms Affected
Humans and other mammals