Esketamine
Brand names,
Esketamine
Analogs
Esketamine
Brand Names Mixture
Esketamine
Chemical_Formula
C13H16ClNO
Esketamine
RX_link
http://www.rxlist.com/cgi/generic3/ketamine.htm
Esketamine
fda sheet
Esketamine
msds (material safety sheet)
Esketamine
Synthesis Reference
No information avaliable
Esketamine
Molecular Weight
237.725 g/mol
Esketamine
Melting Point
92.5 oC
Esketamine
H2O Solubility
No information avaliable
Esketamine
State
Solid
Esketamine
LogP
3.032
Esketamine
Dosage Forms
Solution
Esketamine
Indication
For use as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation.
Esketamine
Pharmacology
Ketamine is a rapid-acting general anesthetic producing an anesthetic state characterized by profound analgesia, normal pharyngeal-laryngeal reflexes, normal or slightly enhanced skeletal muscle tone, cardiovascular and respiratory stimulation, and occasionally a transient and minimal respiratory depression. Ketamine is indicated as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. The anesthetic state produced by Ketamine has been termed “dissociative anesthesia” in that it appears to selectively interrupt association pathways of the brain before producing somesthetic sensory blockade. It may selectively depress the thalamoneocortical system before significantly obtunding the more ancient cerebral centers and pathways (reticularactivating and limbic systems).
Esketamine
Absorption
Rapidly absorbed following parenteral administration.
Esketamine
side effects and Toxicity
No information avaliable
Esketamine
Patient Information
PATIENT INFORMATION
Follow the links
http://www.rxlist.com/cgi/generic3/ketamine_pi.htm
http://www.rxlist.com/cgi/generic3/ketamine_wcp.htm
http://www.drugs.com/cons/Ketamine.html
Esketamine
Organisms Affected
Humans and other mammals