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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C13H16ClNO
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RX_link
http://www.rxlist.com/cgi/generic3/ketamine.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
237.725 g/mol
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Melting Point
92.5 oC
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H2O Solubility
No information avaliable
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State
Solid
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LogP
3.032
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Dosage Forms
Solution
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Indication
For use as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation.
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Pharmacology
Ketamine is a rapid-acting general anesthetic producing an anesthetic state characterized by profound analgesia, normal pharyngeal-laryngeal reflexes, normal or slightly enhanced skeletal muscle tone, cardiovascular and respiratory stimulation, and occasionally a transient and minimal respiratory depression. Ketamine is indicated as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. The anesthetic state produced by Ketamine has been termed “dissociative anesthesia” in that it appears to selectively interrupt association pathways of the brain before producing somesthetic sensory blockade. It may selectively depress the thalamoneocortical system before significantly obtunding the more ancient cerebral centers and pathways (reticularactivating and limbic systems).
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Absorption
Rapidly absorbed following parenteral administration.
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side effects and Toxicity
No information avaliable
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Patient Information
PATIENT INFORMATION
Follow the links
http://www.rxlist.com/cgi/generic3/ketamine_pi.htm
http://www.rxlist.com/cgi/generic3/ketamine_wcp.htm
http://www.drugs.com/cons/Ketamine.html
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Organisms Affected
Humans and other mammals