Butoconazole
Butoconazole Brand names, Butoconazole Analogs
Butoconazole Brand Names Mixture
- No information avaliable
Butoconazole Chemical_Formula
C19H17Cl3N2S
Butoconazole RX_link
http://www.rxlist.com/cgi/generic2/butoconazole.htm
Butoconazole fda sheet
Butoconazole msds (material safety sheet)
Butoconazole Synthesis Reference
No information avaliable
Butoconazole Molecular Weight
411.776 g/mol
Butoconazole Melting Point
Melts at about 159°C with decomposition (nitrate salt)
Butoconazole H2O Solubility
Nitrate salt: 0.26 mg/ml (practically insoluble)
Butoconazole State
Solid
Butoconazole LogP
6.512
Butoconazole Dosage Forms
Vaginal cream (2%)
Butoconazole Indication
For the local treatment of vulvovaginal candidiasis (infections caused by Candida)
Butoconazole Pharmacology
Butoconazole is an imidazole derivative that has fungicidal activity in vitro against Candida spp. and has been demonstrated to be clinically effective against vaginal infections due to Candida albicans. Candida albicans has been identified as the predominant species responsible for vulvovaginal candidasis.
Butoconazole Absorption
Following vaginal administration of butoconazole nitrate vaginal cream, 2% to 3 women, 1.7% (range 1.3-2.2%) of the dose was absorbed on average.
Butoconazole side effects and Toxicity
Oral, rat: LD50 = >1720 mg/kg.
Butoconazole Patient Information
Butoconazole Organisms Affected
Fungi, yeast and protozoans
