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Gynazole-1 Brand names, Gynazole-1 Analogs

Gynazole-1 Brand Names Mixture

  • No information avaliable

Gynazole-1 Chemical_Formula


Gynazole-1 RX_link

Gynazole-1 fda sheet

Gynazole-1 FDA

Gynazole-1 msds (material safety sheet)

Gynazole-1 MSDS

Gynazole-1 Synthesis Reference

No information avaliable

Gynazole-1 Molecular Weight

411.776 g/mol

Gynazole-1 Melting Point

Melts at about 159°C with decomposition (nitrate salt)

Gynazole-1 H2O Solubility

Nitrate salt: 0.26 mg/ml (practically insoluble)

Gynazole-1 State


Gynazole-1 LogP


Gynazole-1 Dosage Forms

Vaginal cream (2%)

Gynazole-1 Indication

For the local treatment of vulvovaginal candidiasis (infections caused by Candida)

Gynazole-1 Pharmacology

Butoconazole is an imidazole derivative that has fungicidal activity in vitro against Candida spp. and has been demonstrated to be clinically effective against vaginal infections due to Candida albicans. Candida albicans has been identified as the predominant species responsible for vulvovaginal candidasis.

Gynazole-1 Absorption

Following vaginal administration of butoconazole nitrate vaginal cream, 2% to 3 women, 1.7% (range 1.3-2.2%) of the dose was absorbed on average.

Gynazole-1 side effects and Toxicity

Oral, rat: LD50 = >1720 mg/kg.

Gynazole-1 Patient Information

Gynazole-1 Organisms Affected

Fungi, yeast and protozoans