PharmacyCodes



Butoconazol [INN-Spanish] en es it fr

Butoconazol [INN-Spanish] Brand names, Butoconazol [INN-Spanish] Analogs

Butoconazol [INN-Spanish] Brand Names Mixture

  • No information avaliable

Butoconazol [INN-Spanish] Chemical_Formula

C19H17Cl3N2S

Butoconazol [INN-Spanish] RX_link

http://www.rxlist.com/cgi/generic2/butoconazole.htm

Butoconazol [INN-Spanish] fda sheet

Butoconazol_[INN-Spanish] FDA

Butoconazol [INN-Spanish] msds (material safety sheet)

Butoconazol_[INN-Spanish] MSDS

Butoconazol [INN-Spanish] Synthesis Reference

No information avaliable

Butoconazol [INN-Spanish] Molecular Weight

411.776 g/mol

Butoconazol [INN-Spanish] Melting Point

Melts at about 159°C with decomposition (nitrate salt)

Butoconazol [INN-Spanish] H2O Solubility

Nitrate salt: 0.26 mg/ml (practically insoluble)

Butoconazol [INN-Spanish] State

Solid

Butoconazol [INN-Spanish] LogP

6.512

Butoconazol [INN-Spanish] Dosage Forms

Vaginal cream (2%)

Butoconazol [INN-Spanish] Indication

For the local treatment of vulvovaginal candidiasis (infections caused by Candida)

Butoconazol [INN-Spanish] Pharmacology

Butoconazole is an imidazole derivative that has fungicidal activity in vitro against Candida spp. and has been demonstrated to be clinically effective against vaginal infections due to Candida albicans. Candida albicans has been identified as the predominant species responsible for vulvovaginal candidasis.

Butoconazol [INN-Spanish] Absorption

Following vaginal administration of butoconazole nitrate vaginal cream, 2% to 3 women, 1.7% (range 1.3-2.2%) of the dose was absorbed on average.

Butoconazol [INN-Spanish] side effects and Toxicity

Oral, rat: LD50 = >1720 mg/kg.

Butoconazol [INN-Spanish] Patient Information

Butoconazol [INN-Spanish] Organisms Affected

Fungi, yeast and protozoans