Butoconazole nitrate
Butoconazole nitrate Brand names, Butoconazole nitrate Analogs
Butoconazole nitrate Brand Names Mixture
- No information avaliable
Butoconazole nitrate Chemical_Formula
C19H17Cl3N2S
Butoconazole nitrate RX_link
http://www.rxlist.com/cgi/generic2/butoconazole.htm
Butoconazole nitrate fda sheet
Butoconazole nitrate msds (material safety sheet)
Butoconazole nitrate Synthesis Reference
No information avaliable
Butoconazole nitrate Molecular Weight
411.776 g/mol
Butoconazole nitrate Melting Point
Melts at about 159°C with decomposition (nitrate salt)
Butoconazole nitrate H2O Solubility
Nitrate salt: 0.26 mg/ml (practically insoluble)
Butoconazole nitrate State
Solid
Butoconazole nitrate LogP
6.512
Butoconazole nitrate Dosage Forms
Vaginal cream (2%)
Butoconazole nitrate Indication
For the local treatment of vulvovaginal candidiasis (infections caused by Candida)
Butoconazole nitrate Pharmacology
Butoconazole is an imidazole derivative that has fungicidal activity in vitro against Candida spp. and has been demonstrated to be clinically effective against vaginal infections due to Candida albicans. Candida albicans has been identified as the predominant species responsible for vulvovaginal candidasis.
Butoconazole nitrate Absorption
Following vaginal administration of butoconazole nitrate vaginal cream, 2% to 3 women, 1.7% (range 1.3-2.2%) of the dose was absorbed on average.
Butoconazole nitrate side effects and Toxicity
Oral, rat: LD50 = >1720 mg/kg.
Butoconazole nitrate Patient Information
Butoconazole nitrate Organisms Affected
Fungi, yeast and protozoans
