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Butenafine Brand names, Butenafine Analogs

Butenafine Brand Names Mixture

  • No information avaliable

Butenafine Chemical_Formula


Butenafine RX_link


Butenafine fda sheet

Butenafine FDA

Butenafine msds (material safety sheet)

Butenafine Synthesis Reference

No information avaliable

Butenafine Molecular Weight

317.467 g/mol

Butenafine Melting Point

No information avaliable

Butenafine H2O Solubility

Slightly soluble (HCl salt)

Butenafine State


Butenafine LogP


Butenafine Dosage Forms

Cream (10 mg drug per gram of cream)

Butenafine Indication

For the topical treatment of the following dermatologic infections: tinea (pityriasis) versicolor due to M. furfur, interdigital tinea pedis (athlete’s foot), tinea corporis (ringworm) and tinea cruris (jock itch) due to E. floccosum, T. mentagrophytes, T. rubrum, and T. tonsurans.

Butenafine Pharmacology

Butenafine is an antifungal agent that acts by inhibiting squalene epoxidase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes. It is mainly active against dermatophytes and has superior fungicidal activity against this group of fungi when compared to that of terbinafine, naftifine, tolnaftate, clotrimazole, and bifonazole. It is active also against Candida albicans and this activity is superior to that of terbinafine and naftifine. Butenafine also generates low MICs for Cryptococcus neoformans and Aspergillus spp. as well.

Butenafine Absorption

The total amount absorbed through the skin into the systemic circulation has not been quantified.

Butenafine side effects and Toxicity

No information avaliable

Butenafine Patient Information

Butenafine Organisms Affected