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Brompheniramine Brand names, Brompheniramine Analogs

Brompheniramine Brand Names Mixture

  • Derma-4 Ont (Neomycin Sulfate + Nystatin + Thiostrepton (Antibiotic of a Streptomyces Species) + Triamcinolone Acetonide)
  • Flagystatin (Metronidazole + Nystatin)
  • Kenacomb Cream (Gramicidin + Neomycin Sulfate + Nystatin + Triamcinolone Acetonide)
  • Kenacomb Mild Cream (Gramicidin + Neomycin Sulfate + Nystatin + Triamcinolone Acetonide)
  • Kenacomb Mild Ointment (Gramicidin + Neomycin Sulfate + Nystatin + Triamcinolone Acetonide)
  • Kenacomb Ointment (Gramicidin + Neomycin Sulfate + Nystatin + Triamcinolone Acetonide)
  • Kenacomb Ont (Gramicidin + Neomycin (Neomycin Sulfate) + Nystatin + Triamcinolone Acetonide)
  • Lidecomb Cream (Fluocinonide + Gramicidin + Neomycin Sulfate + Nystatin)
  • Mecomb Crm 0.1% (Gramicidin + Neomycin (Neomycin Sulfate) + Nystatin + Triamcinolone Acetonide)
  • Solvaderm Ointment (Neomycin (Neomycin Sulfate) + Nystatin + Thiostrepton (Antibiotic of a Streptomyces Species) + Triamcinolone Acetonide)

Brompheniramine Chemical_Formula

C16H19BrN2

Brompheniramine RX_link

No information avaliable

Brompheniramine fda sheet

Brompheniramine msds (material safety sheet)

Brompheniramine MSDS

Brompheniramine Synthesis Reference

No information avaliable

Brompheniramine Molecular Weight

319.24 g/mol

Brompheniramine Melting Point

< 25 oC

Brompheniramine H2O Solubility

Freely soluble (maleate salt)

Brompheniramine State

Liquid

Brompheniramine LogP

3.74

Brompheniramine Dosage Forms

Elixir; Liquid; Tablet

Brompheniramine Indication

For the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing.

Brompheniramine Pharmacology

Brompheniramine is an antihistaminergic medication of the propylamine class. It is a first-generation antihistamine. In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Brompheniramine is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

Brompheniramine Absorption

Antihistamines are well absorbed from the gastrointestinal tract after oral administration.

Brompheniramine side effects and Toxicity

Oral, rat: LD50 = 318 mg/kg. Signs of overdose include fast or irregular heartbeat, mental or mood changes, tightness in the chest, and unusual tiredness or weakness.

Brompheniramine Patient Information

Brompheniramine Organisms Affected

Humans and other mammals