Bromopheniramine
Brand names,
Bromopheniramine
Analogs
Bromopheniramine
Brand Names Mixture
- Drixoral Cold & Sinus (Dexbrompheniramine Maleate + Pseudoephedrine Sulfate)
- Drixoral Day/Night - Srt/Tabs (Dexbrompheniramine Maleate + Pseudoephedrine Sulfate)
- Drixoral Syrup (Dexbrompheniramine Maleate + Pseudoephedrine Sulfate)
- Drixtab Tab (Dexbrompheniramine Maleate + Pseudoephedrine Sulfate)
Bromopheniramine
Chemical_Formula
C16H19BrN2
Bromopheniramine
RX_link
http://www.rxlist.com/cgi/pharmclips2.cgi?keyword=%20Dexbrompheniramine
Bromopheniramine
fda sheet
Bromopheniramine
msds (material safety sheet)
Bromopheniramine
Synthesis Reference
No information avaliable
Bromopheniramine
Molecular Weight
319.24 g/mol
Bromopheniramine
Melting Point
No information avaliable
Bromopheniramine
H2O Solubility
No information avaliable
Bromopheniramine
State
Solid
Bromopheniramine
LogP
3.74
Bromopheniramine
Dosage Forms
Tablet
Bromopheniramine
Indication
For treatment and relief of symptoms of allergies, hay fever, and colds
Bromopheniramine
Pharmacology
In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Dexbrompheniramine is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.
Bromopheniramine
Absorption
Antihistamines are well absorbed from the gastrointestinal tract after oral administration.
Bromopheniramine
side effects and Toxicity
Signs of an overdose include fast or irregular heartbeat, mental or mood changes, tightness in the chest, and unusual tiredness or weakness.
Bromopheniramine
Patient Information
Bromopheniramine
Organisms Affected
Humans and other mammals