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Bromodiphenhydramine Brand names, Bromodiphenhydramine Analogs

Bromodiphenhydramine Brand Names Mixture

  • Ambenyl Cough Syrup (Ammonium Chloride + Bromodiphenhydramine Hydrochloride + Codeine Phosphate + Diphenhydramine Hydrochloride + Potassium Guaiacol Sulphonate)

Bromodiphenhydramine Chemical_Formula

C17H20BrNO

Bromodiphenhydramine RX_link

No information avaliable

Bromodiphenhydramine fda sheet

Bromodiphenhydramine msds (material safety sheet)

Bromodiphenhydramine Synthesis Reference

No information avaliable

Bromodiphenhydramine Molecular Weight

334.251 g/mol

Bromodiphenhydramine Melting Point

No information avaliable

Bromodiphenhydramine H2O Solubility

No information avaliable

Bromodiphenhydramine State

Solid

Bromodiphenhydramine LogP

4.549

Bromodiphenhydramine Dosage Forms

Tablet

Bromodiphenhydramine Indication

For management of symptoms related to hay fever and other types of allergy and used to help bring up phlegm, thin secretions, and make a cough productive.

Bromodiphenhydramine Pharmacology

Bromodiphenhydramine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, Bromodiphenhydramine competes with free histamine for binding at HA-receptor sites. Bromodiphenhydramine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of Bromodiphenhydramine. This anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown.

Bromodiphenhydramine Absorption

Well absorbed in the digestive tract.

Bromodiphenhydramine side effects and Toxicity

Signs of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, swelling of face, lips, tongue, or throat.

Bromodiphenhydramine Patient Information

No information avaliable

Bromodiphenhydramine Organisms Affected

Humans and other mammals