Bromdiphenhydramine hydrochloride
Brand names,
Bromdiphenhydramine hydrochloride
Analogs
Bromdiphenhydramine hydrochloride
Brand Names Mixture
- Ambenyl Cough Syrup (Ammonium Chloride + Bromodiphenhydramine Hydrochloride + Codeine Phosphate + Diphenhydramine Hydrochloride + Potassium Guaiacol Sulphonate)
Bromdiphenhydramine hydrochloride
Chemical_Formula
C17H20BrNO
Bromdiphenhydramine hydrochloride
RX_link
No information avaliable
Bromdiphenhydramine hydrochloride
fda sheet
Bromdiphenhydramine hydrochloride
msds (material safety sheet)
Bromdiphenhydramine hydrochloride
Synthesis Reference
No information avaliable
Bromdiphenhydramine hydrochloride
Molecular Weight
334.251 g/mol
Bromdiphenhydramine hydrochloride
Melting Point
No information avaliable
Bromdiphenhydramine hydrochloride
H2O Solubility
No information avaliable
Bromdiphenhydramine hydrochloride
State
Solid
Bromdiphenhydramine hydrochloride
LogP
4.549
Bromdiphenhydramine hydrochloride
Dosage Forms
Tablet
Bromdiphenhydramine hydrochloride
Indication
For management of symptoms related to hay fever and other types of allergy and used to help bring up phlegm, thin secretions, and make a cough productive.
Bromdiphenhydramine hydrochloride
Pharmacology
Bromodiphenhydramine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, Bromodiphenhydramine competes with free histamine for binding at HA-receptor sites. Bromodiphenhydramine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of Bromodiphenhydramine. This anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown.
Bromdiphenhydramine hydrochloride
Absorption
Well absorbed in the digestive tract.
Bromdiphenhydramine hydrochloride
side effects and Toxicity
Signs of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, swelling of face, lips, tongue, or throat.
Bromdiphenhydramine hydrochloride
Patient Information
No information avaliable
Bromdiphenhydramine hydrochloride
Organisms Affected
Humans and other mammals