Bromo-Benadryl Base
Brand names,
Bromo-Benadryl Base
Analogs
Bromo-Benadryl Base
Brand Names Mixture
- Ambenyl Cough Syrup (Ammonium Chloride + Bromodiphenhydramine Hydrochloride + Codeine Phosphate + Diphenhydramine Hydrochloride + Potassium Guaiacol Sulphonate)
Bromo-Benadryl Base
Chemical_Formula
C17H20BrNO
Bromo-Benadryl Base
RX_link
No information avaliable
Bromo-Benadryl Base
fda sheet
Bromo-Benadryl Base
msds (material safety sheet)
Bromo-Benadryl Base
Synthesis Reference
No information avaliable
Bromo-Benadryl Base
Molecular Weight
334.251 g/mol
Bromo-Benadryl Base
Melting Point
No information avaliable
Bromo-Benadryl Base
H2O Solubility
No information avaliable
Bromo-Benadryl Base
State
Solid
Bromo-Benadryl Base
LogP
4.549
Bromo-Benadryl Base
Dosage Forms
Tablet
Bromo-Benadryl Base
Indication
For management of symptoms related to hay fever and other types of allergy and used to help bring up phlegm, thin secretions, and make a cough productive.
Bromo-Benadryl Base
Pharmacology
Bromodiphenhydramine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, Bromodiphenhydramine competes with free histamine for binding at HA-receptor sites. Bromodiphenhydramine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of Bromodiphenhydramine. This anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown.
Bromo-Benadryl Base
Absorption
Well absorbed in the digestive tract.
Bromo-Benadryl Base
side effects and Toxicity
Signs of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, swelling of face, lips, tongue, or throat.
Bromo-Benadryl Base
Patient Information
No information avaliable
Bromo-Benadryl Base
Organisms Affected
Humans and other mammals