Bromdiphenylhydramine Hydrochloride

• Antihistamines
• ATC:D04AA32
• ATC:D04AA33
• ATC:R06AA02

• Ambodryl
• Ambodryl Hydrochloride
• Amodryl
• Bromanautine
• Bromazin
• Bromazin Base
• Bromazine
• Bromazine hydrochloride
• Bromdiphenhydramine
• Bromdiphenhydramine hydrochloride
• Bromdiphenylhydramine Hydrochloride
• Bromo-Benadryl
• Bromo-Benadryl Base
• Bromo-Benzdryl
• Bromodiphenhydramine hydrochloride
• Deserol
• Deserol Base
• Histabromamine
• Neo-Benadryl

• Ambenyl Cough Syrup (Ammonium Chloride + Bromodiphenhydramine Hydrochloride + Codeine Phosphate + Diphenhydramine Hydrochloride + Potassium Guaiacol Sulphonate)

C₁₇H₂₀BrNO

No information avaliable

No information avaliable

334.251 g/mol

No information avaliable

No information avaliable

Solid

4.549

Tablet

For management of symptoms related to hay fever and other types of allergy and used to help bring up phlegm, thin secretions, and make a cough productive.

Bromodiphenhydramine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, Bromodiphenhydramine competes with free histamine for binding at HA-receptor sites. Bromodiphenhydramine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of Bromodiphenhydramine. This anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown.

Well absorbed in the digestive tract.

Signs of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, swelling of face, lips, tongue, or throat.

No information avaliable

Humans and other mammals