Basiliximab
Brand names,
Basiliximab
Analogs
Basiliximab
Brand Names Mixture
Basiliximab
Chemical_Formula
C6378H9844N1698O1997S48
Basiliximab
RX_link
http://www.rxlist.com/cgi/generic2/basiliximab.htm
Basiliximab
fda sheet
Basiliximab
msds (material safety sheet)
Basiliximab
Synthesis Reference
No information avaliable
Basiliximab
Molecular Weight
143801.3
Basiliximab
Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Basiliximab
H2O Solubility
No information avaliable
Basiliximab
State
Liquid
Basiliximab
LogP
-0.473
Basiliximab
Dosage Forms
Powder for solution
Basiliximab
Indication
For prophylactic treatment of kidney transplant rejection
Basiliximab
Pharmacology
Simulect functions as an IL-2 receptor antagonist. Specifically it inhibits IL-2-mediated activation of lymphocytes, a critical pathway in the cellular immune response involved in allograft rejection.
Basiliximab
Absorption
No information avaliable
Basiliximab
side effects and Toxicity
No information avaliable
Basiliximab
Patient Information
No information avaliable
Basiliximab
Organisms Affected
Humans and other mammals