chimeric mouse-human antiCD25
Brand names,
chimeric mouse-human antiCD25
Analogs
chimeric mouse-human antiCD25
Brand Names Mixture
chimeric mouse-human antiCD25
Chemical_Formula
C6378H9844N1698O1997S48
chimeric mouse-human antiCD25
RX_link
http://www.rxlist.com/cgi/generic2/basiliximab.htm
chimeric mouse-human antiCD25
fda sheet
chimeric mouse-human antiCD25
msds (material safety sheet)
chimeric mouse-human antiCD25
Synthesis Reference
No information avaliable
chimeric mouse-human antiCD25
Molecular Weight
143801.3
chimeric mouse-human antiCD25
Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
chimeric mouse-human antiCD25
H2O Solubility
No information avaliable
chimeric mouse-human antiCD25
State
Liquid
chimeric mouse-human antiCD25
LogP
-0.473
chimeric mouse-human antiCD25
Dosage Forms
Powder for solution
chimeric mouse-human antiCD25
Indication
For prophylactic treatment of kidney transplant rejection
chimeric mouse-human antiCD25
Pharmacology
Simulect functions as an IL-2 receptor antagonist. Specifically it inhibits IL-2-mediated activation of lymphocytes, a critical pathway in the cellular immune response involved in allograft rejection.
chimeric mouse-human antiCD25
Absorption
No information avaliable
chimeric mouse-human antiCD25
side effects and Toxicity
No information avaliable
chimeric mouse-human antiCD25
Patient Information
No information avaliable
chimeric mouse-human antiCD25
Organisms Affected
Humans and other mammals