Baciim
Baciim Brand names, Baciim Analogs
Baciim Brand Names Mixture
- No information avaliable
Baciim Chemical_Formula
C66H103N17O16S
Baciim RX_link
http://www.rxlist.com/cgi/generic3/bacit.htm
Baciim fda sheet
Baciim msds (material safety sheet)
Baciim Synthesis Reference
No information avaliable
Baciim Molecular Weight
1422.69 g/mol
Baciim Melting Point
221 - 225 oC
Baciim H2O Solubility
Freely soluble
Baciim State
Solid
Baciim LogP
-1.025
Baciim Dosage Forms
Drug premix; Ointment; Powder; Powder for solution
Baciim Indication
For the treatment of infants with pneumonia and empyema caused by staphylococci shown to be susceptible to the drug. Also used in ointment form for topical treatment of a variety of localized skin and eye infections, as well as for the prevention of wound infections.
Baciim Pharmacology
Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. As a polypeptide, toxic, and difficult to use chemical, Bacitracin doesn't work well orally, however is very effective topically. Bacitracin exerts pronounced antibacterial action in vitro against a variety of gram-positive and a few gram-negative organisms. However, among systemic diseases, only staphylococcal infections qualify for consideration of bacitracin therapy.
Baciim Absorption
Absorption of bacitracin following intramuscular injection is rapid and complete. Absorption from the gastrointestinal tract following oral administration is not appreciable. Absorption following topical application is negligible.
Baciim side effects and Toxicity
Oral, mouse: LD50 = >3750 mg/kg.
Baciim Patient Information
Baciim Organisms Affected
Enteric bacteria and other eubacteria
