Baciguent
Baciguent Brand names, Baciguent Analogs
Baciguent Brand Names Mixture
- No information avaliable
Baciguent Chemical_Formula
C66H103N17O16S
Baciguent RX_link
http://www.rxlist.com/cgi/generic3/bacit.htm
Baciguent fda sheet
Baciguent msds (material safety sheet)
Baciguent Synthesis Reference
No information avaliable
Baciguent Molecular Weight
1422.69 g/mol
Baciguent Melting Point
221 - 225 oC
Baciguent H2O Solubility
Freely soluble
Baciguent State
Solid
Baciguent LogP
-1.025
Baciguent Dosage Forms
Drug premix; Ointment; Powder; Powder for solution
Baciguent Indication
For the treatment of infants with pneumonia and empyema caused by staphylococci shown to be susceptible to the drug. Also used in ointment form for topical treatment of a variety of localized skin and eye infections, as well as for the prevention of wound infections.
Baciguent Pharmacology
Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. As a polypeptide, toxic, and difficult to use chemical, Bacitracin doesn't work well orally, however is very effective topically. Bacitracin exerts pronounced antibacterial action in vitro against a variety of gram-positive and a few gram-negative organisms. However, among systemic diseases, only staphylococcal infections qualify for consideration of bacitracin therapy.
Baciguent Absorption
Absorption of bacitracin following intramuscular injection is rapid and complete. Absorption from the gastrointestinal tract following oral administration is not appreciable. Absorption following topical application is negligible.
Baciguent side effects and Toxicity
Oral, mouse: LD50 = >3750 mg/kg.
Baciguent Patient Information
Baciguent Organisms Affected
Enteric bacteria and other eubacteria
