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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C22H23ClN2O8
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
478.879 g/mol
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Melting Point
No information avaliable
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H2O Solubility
Soluble (at all physiological pH values)
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State
Solid
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LogP
0.315
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Dosage Forms
Capsules
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Indication
For the treatment of infections and to treat acne. It may also be used to treat urinary tract infections, gum disease, and other bacterial infections such as gonorrhea and chlamydia. Lymecycline is also used commonly as a prophylactic treatment for infection by Bacillus anthracis (anthrax). It is also effective against Yersinia pestis and malaria and is also prescribed for the treatment of Lyme disease.
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Pharmacology
Lymecycline is a tetracycline broad-spectrum antibiotic. It is approximately 5000 times more soluble than tetracycline base and is unique amongst tetracyclines in that it is absorbed by the "active transport" process across the intestinal wall, making use of the same fast and efficient mechanism by which carbohydrates are absorbed. It inhibits cell growth by inhibiting translation.
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Absorption
Absorption is fast and efficient. Bioavailability is 100% following oral administration.
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side effects and Toxicity
Adverse effects include nausea, vomiting, diarrhoea, glossitis, enterocolitis, dysphagia, dermatitis, hypersensitivity reactions, proctitis, and vaginitis.
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Patient Information
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Organisms Affected
Enteric bacteria and other eubacteria