5-O-demethyl-22,23-dihydro-avermectin A1a
5-O-demethyl-22,23-dihydro-avermectin A1a Brand names, 5-O-demethyl-22,23-dihydro-avermectin A1a Analogs
5-O-demethyl-22,23-dihydro-avermectin A1a Brand Names Mixture
- No information avaliable
5-O-demethyl-22,23-dihydro-avermectin A1a Chemical_Formula
C12H22O11
5-O-demethyl-22,23-dihydro-avermectin A1a RX_link
http://www.rxlist.com/cgi/generic2/lactulose.htm
5-O-demethyl-22,23-dihydro-avermectin A1a fda sheet
5-O-demethyl-22,23-dihydro-avermectin A1a msds (material safety sheet)
5-O-demethyl-22,23-dihydro-avermectin A1a Synthesis Reference
No information avaliable
5-O-demethyl-22,23-dihydro-avermectin A1a Molecular Weight
342.296 g/mol
5-O-demethyl-22,23-dihydro-avermectin A1a Melting Point
173 - 178 oC
5-O-demethyl-22,23-dihydro-avermectin A1a H2O Solubility
764 mg/mL
5-O-demethyl-22,23-dihydro-avermectin A1a State
Solid
5-O-demethyl-22,23-dihydro-avermectin A1a LogP
-5.19
5-O-demethyl-22,23-dihydro-avermectin A1a Dosage Forms
Liquid; Powder; Solution; Syrup
5-O-demethyl-22,23-dihydro-avermectin A1a Indication
For the treatment of constipation and hepatic encephalopathy.
5-O-demethyl-22,23-dihydro-avermectin A1a Pharmacology
Therapeutically, lactulose has laxative and ammonia-detoxifying actions. In treating constipation lactulose metabolites draw water into the bowel, causing a cathartic effect through osmotic action.
5-O-demethyl-22,23-dihydro-avermectin A1a Absorption
Poorly absorbed from the gastrointestinal tract as no human enzyme that is capable of hydrolysis of this disaccharide is present in human gastrointestinal tissue.
5-O-demethyl-22,23-dihydro-avermectin A1a side effects and Toxicity
LD50=18.2 g/kg (oral, rat). Side effects include diarrhea and resultant dehydration.
5-O-demethyl-22,23-dihydro-avermectin A1a Patient Information
http://www.drugs.com/MTM/labetalol.html
5-O-demethyl-22,23-dihydro-avermectin A1a Organisms Affected
Humans and other mammals
