2-Methylamino-2,3,3-trimethylnorbornane
Brand names,
2-Methylamino-2,3,3-trimethylnorbornane
Analogs
- 2-Methylamino-2,3,3-trimethylnorbornane
- 2-Methylaminoisocamphane
- 2-Norbornanamine, N,2,3,3-tetramethyl-
- 2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
- 3-Methylaminoisocamphane
- 3-Methylaminoisocamphane hydrochloride
- Inversine
- Inversine hydrochloride
- Mecamilamina
- Mecamine
- Mecamine hydrochloride
- Mecamylamine Hydrochloride
- Mekamin hydrochloride
- Mekamine
- Mevasin hydrochloride
- Mevasine
- Revertina
- Versamine
2-Methylamino-2,3,3-trimethylnorbornane
Brand Names Mixture
2-Methylamino-2,3,3-trimethylnorbornane
Chemical_Formula
C11H21N
2-Methylamino-2,3,3-trimethylnorbornane
RX_link
http://www.rxlist.com/cgi/generic2/mecamylamine.htm
2-Methylamino-2,3,3-trimethylnorbornane
fda sheet
2-Methylamino-2,3,3-trimethylnorbornane
msds (material safety sheet)
2-Methylamino-2,3,3-trimethylnorbornane
Synthesis Reference
No information avaliable
2-Methylamino-2,3,3-trimethylnorbornane
Molecular Weight
167.291 g/mol
2-Methylamino-2,3,3-trimethylnorbornane
Melting Point
<25 oC
2-Methylamino-2,3,3-trimethylnorbornane
H2O Solubility
No information avaliable
2-Methylamino-2,3,3-trimethylnorbornane
State
Liquid
2-Methylamino-2,3,3-trimethylnorbornane
LogP
2.477
2-Methylamino-2,3,3-trimethylnorbornane
Dosage Forms
Tablets
2-Methylamino-2,3,3-trimethylnorbornane
Indication
For the treatment of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension
2-Methylamino-2,3,3-trimethylnorbornane
Pharmacology
Mecamylamine is a potent, oral antihypertensive agent and ganglion blocker, and is a secondary amine. Mecamylamine is indicated for the management of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension. Mecamylamine reduces blood pressure in both normotensive and hypertensive individuals. A small oral dosage often produces a smooth and predictable reduction of blood pressure. Although this antihypertensive effect is predominantly orthostatic, the supine blood pressure is also significantly reduced. Mecamylamine crosses the blood-brain and placental barriers.
2-Methylamino-2,3,3-trimethylnorbornane
Absorption
Mecamylamine is almost completely absorbed from the gastrointestinal tract
2-Methylamino-2,3,3-trimethylnorbornane
side effects and Toxicity
No information avaliable
2-Methylamino-2,3,3-trimethylnorbornane
Patient Information
APRD00458_PI.txt
2-Methylamino-2,3,3-trimethylnorbornane
Organisms Affected
Humans and other mammals