Mekamine
Brand names,
Mekamine
Analogs
- 2-Methylamino-2,3,3-trimethylnorbornane
- 2-Methylaminoisocamphane
- 2-Norbornanamine, N,2,3,3-tetramethyl-
- 2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
- 3-Methylaminoisocamphane
- 3-Methylaminoisocamphane hydrochloride
- Inversine
- Inversine hydrochloride
- Mecamilamina
- Mecamine
- Mecamine hydrochloride
- Mecamylamine Hydrochloride
- Mekamin hydrochloride
- Mekamine
- Mevasin hydrochloride
- Mevasine
- Revertina
- Versamine
Mekamine
Brand Names Mixture
Mekamine
Chemical_Formula
C11H21N
Mekamine
RX_link
http://www.rxlist.com/cgi/generic2/mecamylamine.htm
Mekamine
fda sheet
Mekamine
msds (material safety sheet)
Mekamine
Synthesis Reference
No information avaliable
Mekamine
Molecular Weight
167.291 g/mol
Mekamine
Melting Point
<25 oC
Mekamine
H2O Solubility
No information avaliable
Mekamine
State
Liquid
Mekamine
LogP
2.477
Mekamine
Dosage Forms
Tablets
Mekamine
Indication
For the treatment of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension
Mekamine
Pharmacology
Mecamylamine is a potent, oral antihypertensive agent and ganglion blocker, and is a secondary amine. Mecamylamine is indicated for the management of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension. Mecamylamine reduces blood pressure in both normotensive and hypertensive individuals. A small oral dosage often produces a smooth and predictable reduction of blood pressure. Although this antihypertensive effect is predominantly orthostatic, the supine blood pressure is also significantly reduced. Mecamylamine crosses the blood-brain and placental barriers.
Mekamine
Absorption
Mecamylamine is almost completely absorbed from the gastrointestinal tract
Mekamine
side effects and Toxicity
No information avaliable
Mekamine
Patient Information
APRD00458_PI.txt
Mekamine
Organisms Affected
Humans and other mammals