2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
Brand names,
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
Analogs
- 2-Methylamino-2,3,3-trimethylnorbornane
- 2-Methylaminoisocamphane
- 2-Norbornanamine, N,2,3,3-tetramethyl-
- 2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
- 3-Methylaminoisocamphane
- 3-Methylaminoisocamphane hydrochloride
- Inversine
- Inversine hydrochloride
- Mecamilamina
- Mecamine
- Mecamine hydrochloride
- Mecamylamine Hydrochloride
- Mekamin hydrochloride
- Mekamine
- Mevasin hydrochloride
- Mevasine
- Revertina
- Versamine
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
Brand Names Mixture
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
Chemical_Formula
C11H21N
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
RX_link
http://www.rxlist.com/cgi/generic2/mecamylamine.htm
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
fda sheet
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
msds (material safety sheet)
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
Synthesis Reference
No information avaliable
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
Molecular Weight
167.291 g/mol
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
Melting Point
<25 oC
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
H2O Solubility
No information avaliable
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
State
Liquid
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
LogP
2.477
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
Dosage Forms
Tablets
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
Indication
For the treatment of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
Pharmacology
Mecamylamine is a potent, oral antihypertensive agent and ganglion blocker, and is a secondary amine. Mecamylamine is indicated for the management of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension. Mecamylamine reduces blood pressure in both normotensive and hypertensive individuals. A small oral dosage often produces a smooth and predictable reduction of blood pressure. Although this antihypertensive effect is predominantly orthostatic, the supine blood pressure is also significantly reduced. Mecamylamine crosses the blood-brain and placental barriers.
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
Absorption
Mecamylamine is almost completely absorbed from the gastrointestinal tract
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
side effects and Toxicity
No information avaliable
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
Patient Information
APRD00458_PI.txt
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
Organisms Affected
Humans and other mammals