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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C4H7N1O4
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
133.104 g/mol
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Melting Point
230 oC
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H2O Solubility
4.5 g/l
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State
Solid
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LogP
-0.67 +/- 0.36
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Dosage Forms
Capsules and powder
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Indication
There is no support for the claim that aspartates are exercise performance enhancers, i.e. ergogenic aids.
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Pharmacology
L-aspartate is considered a non-essential amino acid, meaning that, under normal physiological conditions, sufficient amounts of the amino acid are synthesized in the body to meet the body's requirements. L-aspartate is formed by the transamination of the Krebs cycle intermediate oxaloacetate. The amino acid serves as a precursor for synthesis of proteins, oligopeptides, purines, pyrimidines, nucleic acids and L-arginine. L-aspartate is a glycogenic amino acid, and it can also promote energy production via its metabolism in the Krebs cycle. These latter activities were the rationale for the claim that supplemental aspartate has an anti-fatigue effect on skeletal muscle, a claim that was never confirmed.
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Absorption
Absorbed from the small intestine by an active transport process
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side effects and Toxicity
Mild gastrointestinal side effects including diarrhea. LD50 (rat) > 5,000 mg/kg.
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals