Thein
Category
Thein Brand names, Thein Analogs
Thein Brand Names Mixture
Thein Chemical_Formula
C8H10N4O2
Thein RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Thein fda sheet
Thein msds (material safety sheet)
Thein Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Thein Molecular Weight
194.191 g/mol
Thein Melting Point
238 oC
Thein H2O Solubility
22 mg/ml
Thein State
Solid
Thein LogP
-0.07
Thein Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Thein Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Thein Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Thein Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Thein side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Thein Patient Information
Thein Organisms Affected
Humans and other mammals
