Koffein
Category
Koffein Brand names, Koffein Analogs
Koffein Brand Names Mixture
Koffein Chemical_Formula
C8H10N4O2
Koffein RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Koffein fda sheet
Koffein msds (material safety sheet)
Koffein Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Koffein Molecular Weight
194.191 g/mol
Koffein Melting Point
238 oC
Koffein H2O Solubility
22 mg/ml
Koffein State
Solid
Koffein LogP
-0.07
Koffein Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Koffein Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Koffein Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Koffein Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Koffein side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Koffein Patient Information
Koffein Organisms Affected
Humans and other mammals
