Coffeine
Category
Coffeine Brand names, Coffeine Analogs
Coffeine Brand Names Mixture
Coffeine Chemical_Formula
C8H10N4O2
Coffeine RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Coffeine fda sheet
Coffeine msds (material safety sheet)
Coffeine Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Coffeine Molecular Weight
194.191 g/mol
Coffeine Melting Point
238 oC
Coffeine H2O Solubility
22 mg/ml
Coffeine State
Solid
Coffeine LogP
-0.07
Coffeine Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Coffeine Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Coffeine Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Coffeine Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Coffeine side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Coffeine Patient Information
Coffeine Organisms Affected
Humans and other mammals
