Caffein
Category
Caffein Brand names, Caffein Analogs
Caffein Brand Names Mixture
Caffein Chemical_Formula
C8H10N4O2
Caffein RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Caffein fda sheet
Caffein msds (material safety sheet)
Caffein Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Caffein Molecular Weight
194.191 g/mol
Caffein Melting Point
238 oC
Caffein H2O Solubility
22 mg/ml
Caffein State
Solid
Caffein LogP
-0.07
Caffein Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Caffein Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Caffein Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Caffein Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Caffein side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Caffein Patient Information
Caffein Organisms Affected
Humans and other mammals
