CFF
Category
CFF Brand names, CFF Analogs
CFF Brand Names Mixture
CFF Chemical_Formula
C8H10N4O2
CFF RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
CFF fda sheet
CFF msds (material safety sheet)
CFF Synthesis Reference
U.S. Pat. 2,508,545 (1950)
CFF Molecular Weight
194.191 g/mol
CFF Melting Point
238 oC
CFF H2O Solubility
22 mg/ml
CFF State
Solid
CFF LogP
-0.07
CFF Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
CFF Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
CFF Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
CFF Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
CFF side effects and Toxicity
LD50=127 mg/kg (orally in mice)
CFF Patient Information
CFF Organisms Affected
Humans and other mammals
