Terazosin HCl
Category
Terazosin HCl Brand names, Terazosin HCl Analogs
Terazosin HCl Brand Names Mixture
Terazosin HCl Chemical_Formula
C19H25N5O4
Terazosin HCl RX_link
http://www.rxlist.com/cgi/generic/teraz.htm
Terazosin HCl fda sheet
Terazosin HCl msds (material safety sheet)
Terazosin HCl Synthesis Reference
M. Winn et al., U.S. Pat. 4,026,894 (1977)
Terazosin HCl Molecular Weight
387.433 g/mol
Terazosin HCl Melting Point
273 oC
Terazosin HCl H2O Solubility
29.7mg/mL
Terazosin HCl State
Solid
Terazosin HCl LogP
0.875
Terazosin HCl Dosage Forms
Tablet
Terazosin HCl Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) and also for hypertension.
Terazosin HCl Pharmacology
Terazosin, classified as a quinazoline, is similar to doxazosin and prazosin. As an alpha-adrenergic blocking agent, terazosin is used to treat hypertension and benign prostatic hypertrophy (BPH). Terazosin produces vasodilation and reduces peripheral resistance but in general has slight effect on cardiac output. Antihypertensive effect with chronic dosing is usually not accompanied by reflex tachycardia.
Terazosin HCl Absorption
Essentially completely absorbed in man (90% bioavailability).
Terazosin HCl side effects and Toxicity
LD50=259.3mg/kg (i.v. in mice)
Terazosin HCl Patient Information
Terazosin HCl Organisms Affected
Humans and other mammals
