Flumarc
Category
Flumarc Brand names, Flumarc Analogs
Flumarc Brand Names Mixture
Flumarc Chemical_Formula
C19H25N5O4
Flumarc RX_link
http://www.rxlist.com/cgi/generic/teraz.htm
Flumarc fda sheet
Flumarc msds (material safety sheet)
Flumarc Synthesis Reference
M. Winn et al., U.S. Pat. 4,026,894 (1977)
Flumarc Molecular Weight
387.433 g/mol
Flumarc Melting Point
273 oC
Flumarc H2O Solubility
29.7mg/mL
Flumarc State
Solid
Flumarc LogP
0.875
Flumarc Dosage Forms
Tablet
Flumarc Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) and also for hypertension.
Flumarc Pharmacology
Terazosin, classified as a quinazoline, is similar to doxazosin and prazosin. As an alpha-adrenergic blocking agent, terazosin is used to treat hypertension and benign prostatic hypertrophy (BPH). Terazosin produces vasodilation and reduces peripheral resistance but in general has slight effect on cardiac output. Antihypertensive effect with chronic dosing is usually not accompanied by reflex tachycardia.
Flumarc Absorption
Essentially completely absorbed in man (90% bioavailability).
Flumarc side effects and Toxicity
LD50=259.3mg/kg (i.v. in mice)
Flumarc Patient Information
Flumarc Organisms Affected
Humans and other mammals
