Heitrin
Category
Heitrin Brand names, Heitrin Analogs
Heitrin Brand Names Mixture
Heitrin Chemical_Formula
C19H25N5O4
Heitrin RX_link
http://www.rxlist.com/cgi/generic/teraz.htm
Heitrin fda sheet
Heitrin msds (material safety sheet)
Heitrin Synthesis Reference
M. Winn et al., U.S. Pat. 4,026,894 (1977)
Heitrin Molecular Weight
387.433 g/mol
Heitrin Melting Point
273 oC
Heitrin H2O Solubility
29.7mg/mL
Heitrin State
Solid
Heitrin LogP
0.875
Heitrin Dosage Forms
Tablet
Heitrin Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) and also for hypertension.
Heitrin Pharmacology
Terazosin, classified as a quinazoline, is similar to doxazosin and prazosin. As an alpha-adrenergic blocking agent, terazosin is used to treat hypertension and benign prostatic hypertrophy (BPH). Terazosin produces vasodilation and reduces peripheral resistance but in general has slight effect on cardiac output. Antihypertensive effect with chronic dosing is usually not accompanied by reflex tachycardia.
Heitrin Absorption
Essentially completely absorbed in man (90% bioavailability).
Heitrin side effects and Toxicity
LD50=259.3mg/kg (i.v. in mice)
Heitrin Patient Information
Heitrin Organisms Affected
Humans and other mammals
