Blavin
Category
Blavin Brand names, Blavin Analogs
Blavin Brand Names Mixture
Blavin Chemical_Formula
C19H25N5O4
Blavin RX_link
http://www.rxlist.com/cgi/generic/teraz.htm
Blavin fda sheet
Blavin msds (material safety sheet)
Blavin Synthesis Reference
M. Winn et al., U.S. Pat. 4,026,894 (1977)
Blavin Molecular Weight
387.433 g/mol
Blavin Melting Point
273 oC
Blavin H2O Solubility
29.7mg/mL
Blavin State
Solid
Blavin LogP
0.875
Blavin Dosage Forms
Tablet
Blavin Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) and also for hypertension.
Blavin Pharmacology
Terazosin, classified as a quinazoline, is similar to doxazosin and prazosin. As an alpha-adrenergic blocking agent, terazosin is used to treat hypertension and benign prostatic hypertrophy (BPH). Terazosin produces vasodilation and reduces peripheral resistance but in general has slight effect on cardiac output. Antihypertensive effect with chronic dosing is usually not accompanied by reflex tachycardia.
Blavin Absorption
Essentially completely absorbed in man (90% bioavailability).
Blavin side effects and Toxicity
LD50=259.3mg/kg (i.v. in mice)
Blavin Patient Information
Blavin Organisms Affected
Humans and other mammals
