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Napton Brand names, Napton Analogs

Napton Brand Names Mixture

  • Apo-Chlorax Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Corium Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Librax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Pro Chlorax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)

Napton Chemical_Formula

C16H14ClN3O

Napton RX_link

http://www.rxlist.com/cgi/generic/chlordia.htm

Napton fda sheet

Napton msds (material safety sheet)

Napton MSDS

Napton Synthesis Reference

No information avaliable

Napton Molecular Weight

299.755 g/mol

Napton Melting Point

236.2 oC

Napton H2O Solubility

2000 mg/L

Napton State

Solid

Napton LogP

2.853

Napton Dosage Forms

Capsule (5 mg, 10 mg or 25 mg)

Napton Indication

For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.

Napton Pharmacology

Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The precise mechanism of action is not known. The drug blocks EEG arousal from stimulation of the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dosage which effectively blocked the vicious reaction was well below the dose which caused sedation in these animals.

Napton Absorption

No information avaliable

Napton side effects and Toxicity

LD50=537 mg/kg (Orally in rats). Signs of overdose include respiratory depression, muscle weakness, somnolence (general depressed activity).

Napton Patient Information

Napton Organisms Affected

Humans and other mammals