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Napoton Brand names, Napoton Analogs

Napoton Brand Names Mixture

  • Apo-Chlorax Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Corium Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Librax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Pro Chlorax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)

Napoton Chemical_Formula

C16H14ClN3O

Napoton RX_link

http://www.rxlist.com/cgi/generic/chlordia.htm

Napoton fda sheet

Napoton msds (material safety sheet)

Napoton MSDS

Napoton Synthesis Reference

No information avaliable

Napoton Molecular Weight

299.755 g/mol

Napoton Melting Point

236.2 oC

Napoton H2O Solubility

2000 mg/L

Napoton State

Solid

Napoton LogP

2.853

Napoton Dosage Forms

Capsule (5 mg, 10 mg or 25 mg)

Napoton Indication

For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.

Napoton Pharmacology

Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The precise mechanism of action is not known. The drug blocks EEG arousal from stimulation of the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dosage which effectively blocked the vicious reaction was well below the dose which caused sedation in these animals.

Napoton Absorption

No information avaliable

Napoton side effects and Toxicity

LD50=537 mg/kg (Orally in rats). Signs of overdose include respiratory depression, muscle weakness, somnolence (general depressed activity).

Napoton Patient Information

Napoton Organisms Affected

Humans and other mammals