Methaminodiazepoxide en es it fr

Methaminodiazepoxide Brand names, Methaminodiazepoxide Analogs

Methaminodiazepoxide Brand Names Mixture

  • Apo-Chlorax Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Corium Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Librax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Pro Chlorax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)

Methaminodiazepoxide Chemical_Formula


Methaminodiazepoxide RX_link

Methaminodiazepoxide fda sheet

Methaminodiazepoxide msds (material safety sheet)

Methaminodiazepoxide MSDS

Methaminodiazepoxide Synthesis Reference

No information avaliable

Methaminodiazepoxide Molecular Weight

299.755 g/mol

Methaminodiazepoxide Melting Point

236.2 oC

Methaminodiazepoxide H2O Solubility

2000 mg/L

Methaminodiazepoxide State


Methaminodiazepoxide LogP


Methaminodiazepoxide Dosage Forms

Capsule (5 mg, 10 mg or 25 mg)

Methaminodiazepoxide Indication

For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.

Methaminodiazepoxide Pharmacology

Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The precise mechanism of action is not known. The drug blocks EEG arousal from stimulation of the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dosage which effectively blocked the vicious reaction was well below the dose which caused sedation in these animals.

Methaminodiazepoxide Absorption

No information avaliable

Methaminodiazepoxide side effects and Toxicity

LD50=537 mg/kg (Orally in rats). Signs of overdose include respiratory depression, muscle weakness, somnolence (general depressed activity).

Methaminodiazepoxide Patient Information

Methaminodiazepoxide Organisms Affected

Humans and other mammals