Librelease en es it fr

Librelease Brand names, Librelease Analogs

Librelease Brand Names Mixture

  • Apo-Chlorax Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Corium Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Librax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Pro Chlorax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)

Librelease Chemical_Formula

C16H14ClN3O

Librelease RX_link

http://www.rxlist.com/cgi/generic/chlordia.htm

Librelease fda sheet

Librelease msds (material safety sheet)

Librelease MSDS

Librelease Synthesis Reference

No information avaliable

Librelease Molecular Weight

299.755 g/mol

Librelease Melting Point

236.2 oC

Librelease H2O Solubility

2000 mg/L

Librelease State

Solid

Librelease LogP

2.853

Librelease Dosage Forms

Capsule (5 mg, 10 mg or 25 mg)

Librelease Indication

For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.

Librelease Pharmacology

Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The precise mechanism of action is not known. The drug blocks EEG arousal from stimulation of the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dosage which effectively blocked the vicious reaction was well below the dose which caused sedation in these animals.

Librelease Absorption

No information avaliable

Librelease side effects and Toxicity

LD50=537 mg/kg (Orally in rats). Signs of overdose include respiratory depression, muscle weakness, somnolence (general depressed activity).

Librelease Patient Information

Librelease Organisms Affected

Humans and other mammals