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Chloridazepoxide Brand names, Chloridazepoxide Analogs

Chloridazepoxide Brand Names Mixture

  • Apo-Chlorax Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Corium Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Librax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Pro Chlorax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)

Chloridazepoxide Chemical_Formula

C16H14ClN3O

Chloridazepoxide RX_link

http://www.rxlist.com/cgi/generic/chlordia.htm

Chloridazepoxide fda sheet

Chloridazepoxide msds (material safety sheet)

Chloridazepoxide MSDS

Chloridazepoxide Synthesis Reference

No information avaliable

Chloridazepoxide Molecular Weight

299.755 g/mol

Chloridazepoxide Melting Point

236.2 oC

Chloridazepoxide H2O Solubility

2000 mg/L

Chloridazepoxide State

Solid

Chloridazepoxide LogP

2.853

Chloridazepoxide Dosage Forms

Capsule (5 mg, 10 mg or 25 mg)

Chloridazepoxide Indication

For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.

Chloridazepoxide Pharmacology

Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The precise mechanism of action is not known. The drug blocks EEG arousal from stimulation of the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dosage which effectively blocked the vicious reaction was well below the dose which caused sedation in these animals.

Chloridazepoxide Absorption

No information avaliable

Chloridazepoxide side effects and Toxicity

LD50=537 mg/kg (Orally in rats). Signs of overdose include respiratory depression, muscle weakness, somnolence (general depressed activity).

Chloridazepoxide Patient Information

Chloridazepoxide Organisms Affected

Humans and other mammals