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Acti-Hemosyn Caplet (Copper (Copper Malate, Copper Fumarate, Copper Citrate, Copper Succinate, Copper Glutarate) + D-Pantothenic Acid (Calcium D-Pantothenate) + Folic Acid + Iodine (Kelp) + Iron (Ferrous Fumarate, Ferrous Citrate, Iron Malate, Iron Glutarate, Ferrous Succinate) + Manganese (Manganese Citrate, Manganese Fumarate, Manganese Malate, Manganese Succinate, Manganese Glutarate) + Nicotinic Acid + Vitamin B1 (Thiamine Hydrochloride) + Vitamin B12 (Cobamamide) + Vitamin B12 (Hydroxocobalamin) + Vitamin B2 (Riboflavin-5-Phosphate) + Vitamin B6 (Pyridoxal-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride) + Vitamin C (Calcium Ascorbate)) Acti-Hydroxo/Dibencoz 500 + Folic Acid Tab (Folic Acid + Vitamin B12 (Cobamamide, Hydroxocobalamin)) Acti-Multiveg Caplet (Beta-Carotene + Biotin + Calcium (Calcium Organic Complex) + Choline Citrate + Chromium (Chromium Organic Complex) + Copper (Copper Organic Complex) + D-Pantothenic Acid (Calcium D-Pantothenate) + Dl-Methionine + Folic Acid + Inositol + Iodine (Kelp) + Iron (Iron Organic Complex) + Magnesium (Magnesium Organic Complex) + Manganese (Manganese Organic Complex) + Molybdenum (Molybdenum Organic Complex) + Nicotinamide + Nicotinic Acid + Potassium (Potassium Organic Complex) + Selenium (Selenium Organic Complex) + Vanadium (Vanadium Organic Complex) + Vitamin a (Vitamin a Palmitate) + Vitamin B1 (Thiamine Hydrochloride) + Vitamin B12 (Hydroxocobalamin) + Vitamin B2 + Vitamin B2 (Riboflavin 5'-Phosphate Sodium) + Vitamin B6 (Pyridoxal-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride) + Vitamin C + Vitamin D3 + Vitamin E (D-Alpha Tocopheryl Acid Succinate) + Zinc (Zinc Organic Complex)) Awesome Nubears - Tablet (Beta-Carotene (Provitamin a) + Biotin + Calcium (Calcium Citrate, Calcium Fumarate, Calcium Malate, Calcium Succinate, Calcium Glutarate) + Choline Citrate + Copper (Copper Citrate, Copper Fumarate, Copper Malate, Copper Succinate, Copper Glutarate) + D-Alpha Tocopheryl Acid Succinate + D-Pantothenic Acid (Calcium D-Pantothenate) + Folic Acid + Inositol + Iodine (Kelp) + Iron (Iron Citrate, Ferrous Fumarate, Iron Malate, Ferrous Succinate, Iron Glutarate) + Magnesium (Magnesium Citrate, Magnesium Oxide, Magnesium Malate, Magnesium Succinate, Magnesium Glutarate, Magnesium Fumarate) + Manganese (Manganese Citrate, Manganese Fumarate, Manganese Malate, Manganese Succinate, Manganese Glutarate) + Nicotinamide + Potassium (Potassium Citrate, Potassium Fumarate, Potassium Malate, Potassium Succinate, Potassium Glutarate) + Thiamine Hydrochloride + Vitamin B12 (Hydroxocobalamin, Dibencozide) + Vitamin B2 (Riboflavin, Riboflavin-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride, Pyridoxine 5' Phosphate) + Vitamin C (Ascorbic Acid, Calcium Ascorbate) + Vitamin D3 + Zinc (Zinc Citrate, Zinc Fumarate, Zinc Malate, Zinc Succinate, Zinc Glutarate)) Awesome Nubears Tablet (Beta-Carotene + Biotin + Calcium (Calcium Citrate) + Choline + Copper Fumarate (Copper Fumarate) + D-Pantothenic Acid (Calcium D-Pantothenate) + Folic Acid + Inositol (Choline Citrate) + Iodine (Kelp) + Iron (Ferrous Fumarate) + Magnesium (Magnesium Citrate) + Manganese (Manganese Citrate) + Nicotinamide + Potassium (Potassium Citrate) + Vitamin B1 (Thiamine Hydrochloride) + Vitamin B12 (Hydroxocobalamin) + Vitamin B2 + Vitamin B6 (Pyridoxine Hydrochloride) + Vitamin C (Calcium Ascorbate) + Vitamin D3 + Vitamin E (D-Alpha Tocopheryl Acid Succinate) + Zinc (Zinc Citrate)) Magnum Plus Caplet (Beta-Carotene + Biotin + Calcium (Calcium Citrate, Calcium Fumarate, Calcium Malate, Calcium Succinate, Calcium Glutarate) + Choline (Choline Citrate) + Chromium (Chromium Citrate, Chromium Fumarate, Chromium Malate, Chromium Succinate, Chromium Glutarate) + Copper (Copper Citrate, Copper Fumarate, Copper Malate, Copper Succinate, Copper Glutarate) + D-Alpha Tocopheryl Acid Succinate + D-Pantothenic Acid (Calcium D-Pantothenate) + Dl-Methionine + Folic Acid + Inositol + Iodine + Iron (Ferrous Fumarate, Iron Citrate, Iron Malate, Ferrous Succinate, Iron Glutarate) + Magnesium (Magnesium Citrate, Magnesium Fumarate, Magnesium Malate, Magnesium Succinate, Magnesium Glutarate, Magnesium Oxide) + Manganese (Manganese Citrate, Manganese Fumarate, Manganese Malate, Manganese Succinate, Manganese Glutarate) + Molybdenum (Molybdenum Citrate, Molybdenum Fumarate, Molybdenum Malate, Molybdenum Succinate, Molybdenum Glutarate) + Nicotinamide + Nicotinic Acid + Potassium (Potassium Citrate, Potassium Fumarate, Potassium Malate, Potassium Succinate, Potassium Glutarate) + Selenium (Selenium Citrate, Selenium Fumarate, Selenium Malate, Selenium Succinate, Selenium Glutarate) + Thiamine Hydrochloride + Vanadium (Vanadium Citrate, Vanadium Fumarate, Vanadium Malate, Vanadium Succinate, Vanadium Glutarate) + Vitamin a Palmitate + Vitamin B12 (Hydroxocobalamin, Dibencozide) + Vitamin B2 (Riboflavin, Riboflavin-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride, Pyridoxine 5' Phosphate) + Vitamin C (Ascorbic Acid, Calcium Ascorbate) + Vitamin D3 + Zinc (Zinc Citrate, Zinc Fumarate, Zinc Malate, Zinc Succinate, Zinc Glutarate)) the Legend Caplet (Beta-Carotene + Biotin + Calcium (Calcium Citrate, Calcium Fumarate, Calcium Malate, Calcium Succinate, Calcium Glutarate) + Choline (Choline Citrate) + Chromium (Chromium Citrate, Chromium Fumarate, Chromium Malate, Chromium Succinate, Chromium Glutarate) + D-Alpha Tocopheryl Acid Succinate + D-Pantothenic Acid (Calcium D-Pantothenate) + Dl-Methionine + Folic Acid + Inositol + Iodine (Kelp) + Magnesium (Magnesium Citrate, Magnesium Oxide, Magnesium Fumarate, Magnesium Malate, Magnesium Succinate, Magnesium Glutarate) + Manganese (Manganese Citrate, Manganese Fumarate, Manganese Malate, Manganese Succinate, Manganese Glutarate) + Molybdenum (Molybdenum Citrate, Molybdenum Fumarate, Molybdenum Succinate, Molybdenum Glutarate, Molybdenum Malate) + Nicotinamide + Nicotinic Acid + Potassium (Potassium Citrate, Potassium Fumarate, Potassium Malate, Potassium Succinate, Potassium Glutarate) + Selenium (Selenium Citrate, Selenium Fumarate, Selenium Malate, Selenium Succinate, Selenium Glutarate) + Thiamine Hydrochloride + Ubidecarenone + Vanadium (Vanadium Citrate, Vanadium Fumarate, Vanadium Malate, Vanadium Succinate, Vanadium Glutarate) + Vitamin a Palmitate + Vitamin B12 (Hydroxocobalamin, Dibencozide) + Vitamin B2 (Riboflavin, Riboflavin-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride, Pyridoxal-5-Phosphate) + Vitamin C (Ascorbic Acid, Calcium Ascorbate) + Vitamin D3 + Zinc (Zinc Citrate, Zinc Fumarate, Zinc Malate, Zinc Succinate, Zinc Glutarate)) the Legend Time Released Caplet (Beta-Carotene + Biotin + Calcium (Calcium Citrate, Calcium Fumarate, Calcium Malate, Calcium Succinate, Calcium Glutarate) + Choline (Choline Citrate) + Chromium (Chromium Citrate, Chromium Fumarate, Chromium Malate, Chromium Succinate, Chromium Glutarate) + Copper (Copper Citrate, Copper Fumarate, Copper Malate, Copper Succinate, Copper Glutarate) + D-Alpha Tocopheryl Acid Succinate + D-Pantothenic Acid (Calcium D-Pantothenate) + Dl-Methionine + Folic Acid + Inositol + Iodine (Kelp) + Iron (Iron Citrate, Ferrous Fumarate, Iron Malate, Ferrous Succinate, Iron Glutarate) + Magnesium (Magnesium Citrate, Magnesium Oxide, Magnesium Fumarate, Magnesium Malate, Magnesium Succinate, Magnesium Glutarate) + Manganese (Manganese Citrate, Manganese Fumarate, Manganese Malate, Manganese Succinate, Manganese Glutarate) + Molybdenum (Molybdenum Citrate, Molybdenum Fumarate, Molybdenum Malate, Molybdenum Succinate, Molybdenum Glutarate) + Nicotinamide + Nicotinic Acid + Potassium (Potassium Citrate, Potassium Fumarate, Potassium Malate, Potassium Succinate, Potassium Glutarate) + Selenium (Selenium Citrate, Selenium Fumarate, Selenium Malate, Selenium Succinate, Selenium Glutarate) + Thiamine Hydrochloride + Ubidecarenone + Vanadium (Vanadium Citrate, Vanadium Fumarate, Vanadium Malate, Vanadium Succinate, Vanadium Glutarate) + Vitamin a Palmitate + Vitamin B12 (Hydroxocobalamin, Dibencozide) + Vitamin B2 (Riboflavin, Riboflavin-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride, Pyridoxal-5-Phosphate) + Vitamin C (Ascorbic Acid, Calcium Ascorbate) + Vitamin D3 + Zinc (Zinc Citrate, Zinc Fumarate, Zinc Malate, Zinc Succinate, Zinc Glutarate)) the Ultimate One - 50plus Women Caplet (Beta-Carotene + Biotin + Calcium (Calcium Citrate, Calcium Fumarate, Calcium Malate, Calcium Succinate, Calcium Glutarate) + Choline (Choline Citrate) + Chromium (Chromium Citrate, Chromium Fumarate, Chromium Malate, Chromium Succinate, Chromium Glutarate) + Copper (Copper Citrate, Copper Fumarate, Copper Malate, Copper Succinate, Copper Glutarate) + D-Alpha Tocopheryl Acid Succinate + D-Pantothenic Acid (Calcium D-Pantothenate) + Dl-Methionine + Folic Acid + Inositol + Iodine (Kelp) + Magnesium (Magnesium Citrate, Magnesium Fumarate, Magnesium Malate, Magnesium Succinate, Magnesium Glutarate, Magnesium Oxide) + Manganese (Manganese Citrate, Manganese Fumarate, Manganese Malate, Manganese Succinate, Manganese Glutarate) + Molybdenum (Molybdenum Citrate, Molybdenum Fumarate, Molybdenum Malate, Molybdenum Succinate, Molybdenum Glutarate) + Nicotinamide + Nicotinic Acid + Potassium (Potassium Citrate, Potassium Fumarate, Potassium Malate, Potassium Succinate, Potassium Glutarate) + Selenium (Selenium Citrate, Selenium Fumarate, Selenium Malate, Selenium Succinate, Selenium Glutarate) + Thiamine Hydrochloride + Ubidecarenone + Vitamin a Palmitate + Vitamin B12 (Hydroxocobalamin, Dibencozide) + Vitamin B2 (Riboflavin, Riboflavin-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride, Pyridoxal-5-Phosphate) + Vitamin C (Ascorbic Acid, Calcium Ascorbate) + Vitamin D3 + Zinc (Zinc Citrate, Zinc Fumarate, Zinc Malate, Zinc Succinate, Zinc Glutarate)) the Ultimate One - Active Men Caplet (Beta-Carotene + Biotin + Calcium (Calcium Citrate, Calcium Fumarate, Calcium Malate, Calcium Succinate, Calcium Glutarate) + Choline (Choline Citrate) + Chromium (Chromium Citrate, Chromium Fumarate, Chromium Malate, Chromium Succinate, Chromium Glutarate) + D-Alpha Tocopheryl Acid Succinate + D-Pantothenic Acid (Calcium D-Pantothenate) + Dl-Methionine + Folic Acid + Inositol + Iodine (Kelp) + Iron (Iron Citrate, Ferrous Fumarate, Iron Malate, Ferrous Succinate, Iron Glutarate) + Magnesium (Magnesium Citrate, Magnesium Fumarate, Magnesium Malate, Magnesium Succinate, Magnesium Glutarate, Magnesium Oxide) + Manganese (Manganese Citrate, Manganese Fumarate, Manganese Succinate, Manganese Glutarate, Manganese Malate) + Molybdenum (Molybdenum Citrate, Molybdenum Fumarate, Molybdenum Malate, Molybdenum Succinate, Molybdenum Glutarate) + Nicotinamide + Nicotinic Acid + Potassium (Potassium Citrate, Potassium Fumarate, Potassium Malate, Potassium Succinate, Potassium Glutarate) + Selenium (Selenium Citrate, Selenium Fumarate, Selenium Malate, Selenium Succinate, Selenium Glutarate) + Thiamine Hydrochloride + Ubidecarenone + Vitamin a Palmitate + Vitamin B12 (Hydroxocobalamin, Dibencozide) + Vitamin B2 (Riboflavin, Riboflavin-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride, Pyridoxine 5' Phosphate) + Vitamin C (Calcium Ascorbate, Ascorbic Acid) + Vitamin D3 + Zinc (Zinc Citrate, Zinc Fumarate, Zinc Succinate, Zinc Glutarate, Zinc Malate)) the Ultimate One - Active Women Caplet (Beta-Carotene + Biotin + Calcium (Calcium Citrate, Calcium Fumarate, Calcium Malate, Calcium Succinate, Calcium Glutarate) + Choline (Choline Citrate) + Chromium (Chromium Citrate, Chromium Fumarate, Chromium Malate, Chromium Succinate, Chromium Glutarate) + Copper (Copper Malate, Copper Citrate, Copper Fumarate, Copper Succinate, Copper Glutarate) + D-Alpha Tocopheryl Acid Succinate + D-Pantothenic Acid (Calcium D-Pantothenate) + Dl-Methionine + Folic Acid + Inositol + Iodine (Kelp) + Iron (Ferrous Fumarate, Iron Citrate, Iron Malate, Ferrous Succinate, Iron Glutarate) + Magnesium (Magnesium Citrate, Magnesium Fumarate, Magnesium Malate, Magnesium Succinate, Magnesium Glutarate, Magnesium Oxide) + Manganese (Manganese Citrate, Manganese Fumarate, Manganese Malate, Manganese Succinate, Manganese Glutarate) + Molybdenum (Molybdenum Citrate, Molybdenum Fumarate, Molybdenum Malate, Molybdenum Succinate, Molybdenum Glutarate) + Nicotinamide + Nicotinic Acid + Potassium (Potassium Citrate, Potassium Fumarate, Potassium Malate, Potassium Succinate, Potassium Glutarate) + Selenium (Selenium Citrate, Selenium Fumarate, Selenium Malate, Selenium Succinate, Selenium Glutarate) + Thiamine Hydrochloride + Ubidecarenone + Vitamin a Palmitate + Vitamin B12 (Hydroxocobalamin, Dibencozide) + Vitamin B2 (Riboflavin, Riboflavin-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride, Pyridoxal-5-Phosphate) + Vitamin C (Ascorbic Acid, Calcium Ascorbate) + Vitamin D3 + Zinc (Zinc Citrate, Zinc Fumarate, Zinc Malate, Zinc Succinate, Zinc Glutarate)) the Ultimate One - Adult Women Caplet (Beta-Carotene + Biotin + Calcium (Calcium Citrate, Calcium Fumarate, Calcium Malate, Calcium Succinate, Calcium Glutarate) + Choline (Choline Citrate) + Chromium (Chromium Citrate, Chromium Fumarate, Chromium Malate, Chromium Succinate, Chromium Glutarate) + Copper (Copper Citrate, Copper Fumarate, Copper Malate, Copper Succinate, Copper Glutarate) + D-Alpha Tocopheryl Acid Succinate + D-Pantothenic Acid (Calcium D-Pantothenate) + Dl-Methionine + Folic Acid + Inositol + Iodine (Kelp) + Iron (Ferrous Fumarate, Iron Citrate, Iron Malate, Ferrous Succinate, Iron Glutarate) + Magnesium (Magnesium Citrate, Magnesium Fumarate, Magnesium Malate, Magnesium Succinate, Magnesium Glutarate, Magnesium Oxide) + Manganese (Manganese Citrate, Manganese Fumarate, Manganese Malate, Manganese Succinate, Manganese Glutarate) + Molybdenum (Molybdenum Citrate, Molybdenum Fumarate, Molybdenum Malate, Molybdenum Succinate, Molybdenum Glutarate) + Nicotinamide + Nicotinic Acid + Potassium (Potassium Citrate, Potassium Fumarate, Potassium Malate, Potassium Succinate, Potassium Glutarate) + Selenium (Selenium Citrate, Selenium Fumarate, Selenium Malate, Selenium Succinate, Selenium Glutarate) + Thiamine Hydrochloride + Ubidecarenone + Vitamin a Palmitate + Vitamin B12 (Hydroxocobalamin, Dibencozide) + Vitamin B2 (Riboflavin, Riboflavin-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride, Pyridoxal-5-Phosphate) + Vitamin C (Ascorbic Acid, Calcium Ascorbate) + Vitamin D3 + Zinc (Zinc Citrate, Zinc Fumarate, Zinc Malate, Zinc Succinate, Zinc Glutarate)) the Ultimate One-50 Plus Men Caplet (Beta-Carotene + Biotin + Calcium (Calcium Citrate, Calcium Fumarate, Calcium Malate, Calcium Succinate, Calcium Glutarate) + Choline (Choline Citrate) + Chromium (Chromium Citrate, Chromium Fumarate, Chromium Malate, Chromium Succinate, Chromium Glutarate) + D-Alpha Tocopheryl Acid Succinate + D-Pantothenic Acid (Calcium D-Pantothenate) + Dl-Methionine + Folic Acid + Inositol + Iodine (Kelp) + Magnesium (Magnesium Citrate, Magnesium Fumarate, Magnesium Malate, Magnesium Succinate, Magnesium Glutarate, Magnesium Oxide) + Manganese (Manganese Citrate, Manganese Fumarate, Manganese Malate, Manganese Succinate, Manganese Glutarate) + Molybdenum (Molybdenum Citrate, Molybdenum Fumarate, Molybdenum Malate, Molybdenum Succinate, Molybdenum Glutarate) + Nicotinamide + Nicotinic Acid + Potassium (Potassium Citrate, Potassium Fumarate, Potassium Malate, Potassium Succinate, Potassium Glutarate) + Selenium (Selenium Citrate, Selenium Fumarate, Selenium Malate, Selenium Succinate, Selenium Glutarate) + Thiamine Hydrochloride + Ubidecarenone + Vitamin a Palmitate + Vitamin B12 (Hydroxocobalamin, Dibencozide) + Vitamin B2 (Riboflavin, Riboflavin-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride, Pyridoxal-5-Phosphate) + Vitamin C (Ascorbic Acid, Calcium Ascorbate) + Vitamin D3 + Zinc (Zinc Citrate, Zinc Fumarate, Zinc Malate, Zinc Succinate, Zinc Glutarate)) Vege 1 Daily Caplet (Beta-Carotene + Biotin + Calcium (Calcium Citrate, Calcium Fumarate, Calcium Malate, Calcium Succinate, Calcium Glutarate) + Choline Citrate + Chromium (Chromium Citrate, Chromium Fumarate, Chromium Malate, Chromium Succinate, Chromium Glutarate) + Copper (Copper Citrate, Copper Fumarate, Copper Malate, Copper Succinate, Copper Glutarate) + D-Pantothenic Acid (Calcium D-Pantothenate) + Dl-Methionine + Folic Acid + Inositol + Iodine (Kelp) + Iron (Ferrous Citrate, Ferrous Fumarate, Iron Malate, Ferrous Succinate, Iron Glutarate) + Magnesium (Magnesium Citrate, Magnesium Fumarate, Magnesium Malate, Magnesium Succinate, Magnesium Glutarate) + Manganese (Manganese Citrate, Manganese Fumarate, Manganese Malate, Manganese Succinate, Manganese Glutarate) + Molybdenum (Molybdenum Citrate, Molybdenum Fumarate, Molybdenum Malate, Molybdenum Succinate, Molybdenum Glutarate) + Nicotinamide + Nicotinic Acid + Potassium (Potassium Citrate, Potassium Fumarate, Potassium Malate, Potassium Succinate, Potassium Glutarate) + Selenium (Selenium Citrate, Selenium Fumarate, Selenium Malate, Selenium Succinate, Selenium Glutarate) + Vanadium (Vanadium Citrate, Vanadium Fumarate, Vanadium Malate, Vanadium Succinate, Vanadium Glutarate) + Vitamin a (Vitamin a Palmitate) + Vitamin B1 (Thiamine Hydrochloride) + Vitamin B12 (Hydroxocobalamin) + Vitamin B2 (Riboflavin-5-Phosphate) + Vitamin B6 (Pyridoxal-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride) + Vitamin C (Calcium Ascorbate) + Vitamin D3 + Vitamin E (D-Alpha Tocopheryl Acid Succinate) + Zinc (Zinc Citrate, Zinc Fumarate, Zinc Malate, Zinc Succinate, Zinc Glutarate))
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Formula chimica
C22H24ClN3O
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RX link
http://www.rxlist.com/cgi/generic/optivar.htm
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FDA foglio
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DMS (foglio di materiale di sicurezza)
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Sintesi di riferimento
Nessuna informazione disponibile
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Peso molecolare
381.898 g/mol
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Temperatura di fusione
225 oC (hydrochloride salt)
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H2O Solubilita
Scarsamente solubile (cloridrato)
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Stato
Solid
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LogP
4.961
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Forme di dosaggio
Soluzione oftalmica (0,05%)
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Indicazione
Per il trattamento del prurito degli occhi associati a congiuntiviti allergiche.
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Farmacologia
Azelastina è un antagonista selettivo relativamente H1 dell'istamina e un inibitore del rilascio di istamina e di altri mediatori dalle cellule (mastociti ad esempio) coinvolti nella risposta allergica. Sulla base di studi in vitro su linee cellulari umane, l'inibizione di altri mediatori coinvolti nelle reazioni allergiche (ad esempio i leucotrieni e PAF) è stata dimostrata con azelastina. Diminuzione chemiotassi e l'attivazione di eosinofili è stata dimostrata.
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Assorbimento
L'assorbimento di somministrazione oculare azelastina seguente è stata relativamente bassa. Biodisponibilità sistemica è di circa il 40% dopo la somministrazione nasale.
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Tossicita
Nessuna informazione disponibile
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Informazioni paziente
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Atto interessato organismi
Gli esseri umani e altri mammiferi