Cardura-4
Categoria
Cardura-4 Marchi, Cardura-4 Analoghi
Cardura-4 Marchi miscela
Cardura-4 Formula chimica
C23H25N5O5
Cardura-4 RX link
http://www.rxlist.com/cgi/generic/doxazo.htm
Cardura-4 FDA foglio
Cardura-4 DMS (foglio di materiale di sicurezza)
Cardura-4 Sintesi di riferimento
SF Campbell, US Pat. 4,188,390 (1980)
Cardura-4 Peso molecolare
451.475 g/mol
Cardura-4 Temperatura di fusione
289-290oC
Cardura-4 H2O Solubilita
24 mg / L
Cardura-4 Stato
Solid
Cardura-4 LogP
1.838
Cardura-4 Forme di dosaggio
Tablet (orale)
Cardura-4 Indicazione
Per il trattamento e la gestione di ipertensione e sintomi di ostruzione urinaria BPH.
Cardura-4 Farmacologia
Doxazosina è un alfa-adrenergici agente bloccante usato per trattare l'ipertensione e l'iperplasia prostatica benigna. Di conseguenza, doxazosina è un inibitore selettivo del sottotipo di recettori alfa1 adrenergici alfa. Nella prostata umana, Doxazosin antagonizza fenilefrina (alfa1 agonista)-indotta contrazioni, in vitro, e si lega con alta affinità per il adrenocettori alpha1c, che si ritiene essere la predominante tipo funzionale nella prostata. Studi in soggetti umani normali hanno dimostrato che Doxazosin competitivo antagonizzata gli effetti pressori di fenilefrina (un agonista alfa1) e l'effetto pressorio sistolico di noradrenalina. L'effetto antipertensivo Doxazosin dei risultati da una diminuzione della resistenza vascolare sistemica e il Doxazosin composto originario è il principale responsabile per l'attività antipertensiva. .
Cardura-4 Assorbimento
65%
Cardura-4 Tossicita
Sintomi di sovradosaggio comprendono ipotensione. LD50 orale è superiore a 1000 mg / kg in topi e ratti.
Cardura-4 Informazioni paziente
Read This:
Before you start taking doxazosin mesylate.
Each time you get a new prescription.
You and your doctor should discuss this treatment and your BPH symptoms before you start taking doxazosin mesylate and at your regular checkups. This leaflet does NOT take the place of discussions with your doctor.
Doxazosin mesylate is used to treat both benign prostatic hyperplasia (BPH) and high blood pressure (hypertension). This leaflet describes doxazosin mesylate as treatment for BPH (although you may be taking doxazosin mesylate for both your BPH and high blood pressure).
Doxazosin mesylate works on a specific type of muscle found in the prostate, causing it to relax. This in turn decreases the pressure within the prostate, thus improving the wflow of urine and your symptoms.
Doxazosin mesylate helps relieve the symptoms of BPH (weak stream, start-and-stop stream, a feeling that your bladder is not completely empty, delay in beginning of urination, need to urinate often during the day and especially at night, and feeling that you must urinate immediately). It does not change the size of the prostate. The prostate may continue to grow; however, a larger prostate is not necessarily related to more symptoms or to worse symptoms. Doxazosin mesylate can decrease your symptoms and improve urinary flow, without decreasing the size of the prostate.
If doxazosin mesylate is helping you, you should notice an effect within 1 to 2 weeks after you start your medication. Doxazosin mesylate has been studied in over 900 patients for up to 2 years and the drug has been shown to continue to work during long-term treatment. Even though you take doxazosin mesylate and it may help you, doxazosin mesylate may not prevent the need for surgery in the future.
Doxazosin mesylate does not affect PSA levels. PSA is the abbreviation for Prostate Specific Antigen. Your doctor may have done a blood test called PSA. You may want to ask your doctor more about this if you have had a PSA test done.
Other Important Facts
You should see an improvement of your symptoms within 1 to 2 weeks. In addition to your other regular checkups you will need to continue seeing your doctor regularly to check your progress regarding your BPH and to monitor your blood pressure.
Doxazosin mesylate is not a treatment for prostate cancer. Your doctor has prescribed doxazosin mesylate for your BPH and not for prostate cancer; however, a man can have BPH and prostate cancer at the same time. Doctors usually recommend that men be checked for prostate cancer once a year when they turn 50 (or 40 if a family member has had prostate cancer). A higher incidence of prostate cancer has been noted in men of African-American descent. These checks should continue even if you are taking doxazosin mesylate.
How To Take Doxazosin Mesylate and What You Should Know While Taking Doxazosin Mesylate for BPH
Doxazosin mesylate can cause a sudden drop in blood pressure after the VERY FIRST DOSE. You may feel dizzy, faint or �light-headed,� especially after you stand up from a lying or sitting position. This is more likely to occur after you've taken the first few doses or if you increase your dose, but can occur at any time while you are taking the drug. It can also occur if you stop taking the drug and then restart treatment. If you feel very dizzy, faint or �light-headed� you should contact your doctor. Your doctor will discuss with you how often you need to visit and how often your blood pressure should be checked.
Your blood pressure should be checked when you start taking doxazosin mesylate even if you do not have high blood pressure (hypertension). Your doctor will discuss with you the details of how blood pressure is measured.
Before you start taking doxazosin mesylate.
Each time you get a new prescription.
You and your doctor should discuss this treatment and your BPH symptoms before you start taking doxazosin mesylate and at your regular checkups. This leaflet does NOT take the place of discussions with your doctor.
Doxazosin mesylate is used to treat both benign prostatic hyperplasia (BPH) and high blood pressure (hypertension). This leaflet describes doxazosin mesylate as treatment for BPH (although you may be taking doxazosin mesylate for both your BPH and high blood pressure).
Doxazosin mesylate works on a specific type of muscle found in the prostate, causing it to relax. This in turn decreases the pressure within the prostate, thus improving the wflow of urine and your symptoms.
Doxazosin mesylate helps relieve the symptoms of BPH (weak stream, start-and-stop stream, a feeling that your bladder is not completely empty, delay in beginning of urination, need to urinate often during the day and especially at night, and feeling that you must urinate immediately). It does not change the size of the prostate. The prostate may continue to grow; however, a larger prostate is not necessarily related to more symptoms or to worse symptoms. Doxazosin mesylate can decrease your symptoms and improve urinary flow, without decreasing the size of the prostate.
If doxazosin mesylate is helping you, you should notice an effect within 1 to 2 weeks after you start your medication. Doxazosin mesylate has been studied in over 900 patients for up to 2 years and the drug has been shown to continue to work during long-term treatment. Even though you take doxazosin mesylate and it may help you, doxazosin mesylate may not prevent the need for surgery in the future.
Doxazosin mesylate does not affect PSA levels. PSA is the abbreviation for Prostate Specific Antigen. Your doctor may have done a blood test called PSA. You may want to ask your doctor more about this if you have had a PSA test done.
Other Important Facts
You should see an improvement of your symptoms within 1 to 2 weeks. In addition to your other regular checkups you will need to continue seeing your doctor regularly to check your progress regarding your BPH and to monitor your blood pressure.
Doxazosin mesylate is not a treatment for prostate cancer. Your doctor has prescribed doxazosin mesylate for your BPH and not for prostate cancer; however, a man can have BPH and prostate cancer at the same time. Doctors usually recommend that men be checked for prostate cancer once a year when they turn 50 (or 40 if a family member has had prostate cancer). A higher incidence of prostate cancer has been noted in men of African-American descent. These checks should continue even if you are taking doxazosin mesylate.
How To Take Doxazosin Mesylate and What You Should Know While Taking Doxazosin Mesylate for BPH
Doxazosin mesylate can cause a sudden drop in blood pressure after the VERY FIRST DOSE. You may feel dizzy, faint or �light-headed,� especially after you stand up from a lying or sitting position. This is more likely to occur after you've taken the first few doses or if you increase your dose, but can occur at any time while you are taking the drug. It can also occur if you stop taking the drug and then restart treatment. If you feel very dizzy, faint or �light-headed� you should contact your doctor. Your doctor will discuss with you how often you need to visit and how often your blood pressure should be checked.
Your blood pressure should be checked when you start taking doxazosin mesylate even if you do not have high blood pressure (hypertension). Your doctor will discuss with you the details of how blood pressure is measured.
Cardura-4 Atto interessato organismi
Gli esseri umani e altri mammiferi
