Trocoxidil en es it fr


Trocoxidil Les marques, Trocoxidil Analogs

Trocoxidil Les marques melange

  • No information avaliable
  • Trocoxidil Formule chimique


    Trocoxidil RX lien

    Trocoxidil FDA fiche

    Trocoxidil FDA

    Trocoxidil msds (fiche de securite des materiaux)

    Trocoxidil MSDS

    Trocoxidil Synthese de reference

    Aucune information disponible

    Trocoxidil Poids moleculaire

    209.248 g/mol

    Trocoxidil Point de fusion

    248 oC

    Trocoxidil H2O Solubilite

    2200 mg / L

    Trocoxidil Etat


    Trocoxidil LogP


    Trocoxidil Formes pharmaceutiques

    Liquid; Tablet

    Trocoxidil Indication

    Pour le traitement de l'hypertension artérielle sévère et dans le traitement topique (repousse) de l'alopécie androgénique chez les hommes et les femmes et la stabilisation de la perte de cheveux chez les patients souffrant d'alopécie androgénique.

    Trocoxidil Pharmacologie

    Le minoxidil est un vasodilatateur efficace par voie orale à action directe périphériques qui réduit systolique élevée et la pression artérielle diastolique en diminuant la résistance vasculaire périphérique. Le minoxidil est également utilisé par voie topique pour traiter l'alopécie androgénétique. Flux sanguin microcirculatoire chez les animaux est amélioré ou maintenu dans tous les lits vasculaires systémiques. Chez l'homme, avant-bras et la résistance vasculaire rénale recul; débit sanguin augmente alors que le débit sanguin rénal et le taux de filtration glomérulaire sont préservés. Le site de l'action prédominante minoxidil est artériel. Venodilation ne se produit pas avec le minoxidil, ainsi, l'hypotension orthostatique est inhabituel de son administration. L'activité antihypertensive du minoxidil est due à son sulfate sulfate de minoxidil métabolite.

    Trocoxidil Absorption

    Le minoxidil est d'au moins 90% absorbé par le tractus gastro-intestinal des animaux de laboratoire et l'homme.

    Trocoxidil Toxicite

    DL50 orale chez le rat a varié de 1321 à 3492 mg / kg; chez la souris, 2456-2648 mg / kg. Les effets secondaires incluent les effets cardiovasculaires associés à l'hypotension tels que le gain de poids soudaine, rythme cardiaque rapide, des évanouissements ou des étourdissements.

    Trocoxidil Information pour les patients

    The patient should be fully aware of the importance of continuing all of his antihypertensive medications and of the nature of symptoms that would suggest fluid overload. A patient brochure has been prepared and is included with each minoxidil package.

    Minoxidil tablets contain minoxidil, a medicine for the treatment of high blood pressure in the patient who has not been controlled or is experiencing unacceptable side effects with other medications. It must usually be taken with other medicines.

    Be absolutely sure to take all of your medicines for high blood pressure according to your doctor's instructions. Do not stop taking minoxidil unless your doctor tells you to. Do not give any of your medicine to other people.

    It is important that you look for the warning signals of certain undesired effects of minoxidil. Call your doctor if they occur. Your doctor will need to see you regularly while you are taking minoxidil. Be sure to keep all your appointments or to arrange for new ones if you must miss one.

    Do not hesitate to call your doctor if any discomforts or problems occur.

    The information here is intended to help you take minoxidil properly. It does not tell you all there is to know about minoxidil. There is a more technical leaflet that you may request from the pharmacist; you may need your doctor's help in understanding parts of that leaflet.

    What is Minoxidil?

    Minoxidil tablets contain minoxidil which is a drug for lowering the blood pressure. It works by relaxing and enlarging certain small blood vessels so that blood flows through them more easily.

    Why lower blood pressure?

    Your doctor has prescribed minoxidil to lower your blood pressure and protect vital parts of your body. Uncontrolled blood pressure can cause stroke, heart failure, blindness, kidney failure and heart attacks.

    Most people with high blood pressure need to take medicines to treat it for their whole lives.

    Who should not take Minoxidil?

    There are many people with high blood pressure, but most of them do not need minoxidil. Minoxidil is used ONLY when your doctor decides that:

    1. your high blood pressure is severe;

    2. your high blood pressure is causing symptoms or damage to vital organs; and

    3. other medicines did not work well enough or had very disturbing side effects.

    Minoxidil should be taken only when a doctor prescribes it. Never give any of your minoxidil tablets, or any other high blood pressure medicine, to a friend or relative.

    Pregnancy: In some cases doctors may prescribe minoxidil for women who are pregnant or who are planning to have children. However, its safe use in pregnancy has not been established. Laboratory animals had a reduced ability to become pregnant and a reduced survival of offspring while taking minoxidil, if you are pregnant or are planning to become pregnant, be sure to tell your doctor.

    How to take minoxidil.

    Usually, your doctor will prescribe two other medicines along with minoxidil. These will help lower blood pressure and will help prevent undesired effects of minoxidil.

    Often, when a medicine like minoxidil lowers blood pressure your body tries to return the blood pressure to the original higher level. It does this by holding on to water and salt (so there will be more fluid to pump) and by making your heart beat faster, To prevent this, your doctor will usually prescribe a water tablet to remove the extra salt and water from your body (a diuretic dye-u-RET-tic) and another medicine to slow your heart beat.

    You must follow your doctor's instructions exactly, taking all the prescribed medicines, in the right amounts, each day. These medicines will help keep your blood pressure down. The water tablet and heart beat medicine will help prevent the undesired effects of minoxidil.

    Minoxidil tablets come in two strengths (2 1/2 milligrams and 10 milligrams) that are marked on each tablet. Pay close attention to the tablet markings to be sure you are taking the correct strength. Your doctor may prescribe half a tablet, the tablets are scored (partly cut on one side) so that you can easily break them.

    When you first start taking minoxidil, your doctor may need to see you often in order to adjust your dosage. Take all your medicine according to the schedule prescribed by your doctor. Do not skip any doses. If you should forget a dose of minoxidil, wait until it is time for your next dose, then continue with your regular schedule, Remember: do not stop taking minoxidil, or any other, high blood pressure medicines, without checking with your doctor. Make sure that any doctor treating or examining you knows that you are taking high blood pressure medicines, including minoxidil.


    Even if you take all your medicines correctly, minoxidil tablets may cause undesired effects. Some of these are serious and you should be on the lookout for them. If any of the following warning signals occur, you must call your doctor immediately:

    1. Increase in heart rate - You should measure your heart rate by counting your pulse rate while you are resting. If you have an increase of 20 beats or more a minute over your normal pulse, contact your doctor immediately. if you do not know how to take your pulse rate, ask your doctor. Also ask your doctor how often to check your pulse.

    2. Rapid weight gain of more than 5 pounds - You should weigh yourself daily. If you quickly gain five or more pounds or if there is any swelling or puffiness in the face, hands, ankles, or stomach area, this could be a sign that you are retaining body fluids. Your doctor may have to change your drugs or change the dose of your drugs. You may also need to reduce the amount of salt you eat. A smaller weight gain (2 to 3 pounds) often occurs when treatment is started. You may lose this extra weight with continued treatment.

    3. Increased difficulty in breathing, especially when lying down. This too may be due to an increase of body fluids. It can also happen because your high blood pressure is getting worse. In either case, you might require treatment with other medicines.

    4. New or worsening of pain in the chest, arm, or shoulder or signs of severe indigestion - These could be signs of serious heart problems.

    5. Dizziness, lightheadedness or fainting - These can be signs of high blood pressure or they may be side effect from one of the medicine. Your doctor may need to change or adjust the dosage of the medicines you are taking.


    Minoxidil tablets can cause other undesired effects such as nausea and/or vomiting that are annoying but not dangerous. Do not stop taking the drug because of these other undesired effects without talking to your doctor.

    Hair growth: About 8 out of every 10 patients who have taken minoxidil noticed that fine body hair grew darker or longer on certain parts of the body. This happened about 3 to 6 weeks after beginning treatment. The hair may first be noticed on the forehead and temples, between the eyebrows or on the upper part of the cheeks. Later, hair may grow on the back, arms, legs, or scalp. Although hair growth may not be noticeable to some patients, it often is bothersome in women and children. Unwanted hair can be controlled with a hair remover or by shaving. The extra hair is not permanent, it disappears within 1 to 6 months of stopping minoxidil.Nevertheless, you should not stop taking minoxidil without first talking to your doctor.

    A few patients have developed a rash or breast tenderness while taking minoxidil tablets, but this is unusual.

    Store at controlled room temperature 15°-30°C (59°-86°F).

    CAUTION: Federal law prohibits dispensing without prescription.

    Trocoxidil Organismes affectes

    Les humains et autres mammifères