Categorie
Daypro Alta
Les marques,
Daypro Alta
Analogs
Daypro Alta
Les marques melange
No information avaliable
Daypro Alta
Formule chimique
C18H15NO3
Daypro Alta
RX lien
http://www.rxlist.com/cgi/generic/oxaproz.htm
Daypro Alta
FDA fiche
Daypro Alta
msds (fiche de securite des materiaux)
Daypro Alta
Synthese de reference
Aucune information disponible
Daypro Alta
Poids moleculaire
293.317 g/mol
Daypro Alta
Point de fusion
158 - 159 oC
Daypro Alta
H2O Solubilite
Insolubles
Daypro Alta
Etat
Solid
Daypro Alta
LogP
4.8
Daypro Alta
Formes pharmaceutiques
Tablet
Daypro Alta
Indication
Utilisé pour soulager l'inflammation, l'enflure, la raideur et des douleurs articulaires associées à l'arthrite rhumatoïde et l'arthrose.
Daypro Alta
Pharmacologie
Oxaprozine est un médicament anti-inflammatoires non stéroïdiens (AINS) avec des propriétés analgésiques et antipyrétiques. Oxaprozine est utilisé pour traiter l'arthrite rhumatoïde, l'arthrose, la dysménorrhée, et pour soulager la douleur modérée.
Daypro Alta
Absorption
Oxaprozine est de 95% après administration orale. Les aliments peuvent réduire le taux d'absorption de l'oxaprozine, mais le degré d'absorption est inchangé. Les antiacides ne modifient pas sensiblement l'ampleur et la vitesse d'absorption de l'oxaprozine.
Daypro Alta
Toxicite
Oral, souris: DL50 = 1210 mg / kg; orale, lapin: DL50 = 172 mg / kg; voie orale, rat: DL50 = 4470 mg / kg
Daypro Alta
Information pour les patients
Daypro, like other drugs of its class, can cause discomfort and, rarely, more serious side effects, such as
gastrointestinal bleeding, which may result in hospitalization and even fatal outcomes. Although serious
gastrointestinal tract ulcerations and bleeding can occur without warning symptoms, patients should be alert for the
signs and symptoms of ulcerations and bleeding, and should ask for medical advice when observing any indicative sign
or symptoms. Patients should be apprised of the importance of this follow-up.
Patients should report to their physicians the signs or symptoms of gastrointestinal ulceration or bleeding, skin
rash, weight gain, or edema.
Patients should be informed of the warning signs and symptoms of hepatotoxicity (e.g., nausea, fatigue, lethargy,
pruritus, jaundice, right upper quadrant tenderness, and “flu-like” symptoms). If these occur, patients
should be instructed to stop therapy and seek immediate medical therapy.
Patients should also be instructed to seek immediate emergency help in the case of an anaphylactoid reaction.
In late pregnancy, as with other NSAIDs, Daypro should be avoided because it will cause premature closure of the
ductus arteriosus.
Daypro Alta
Organismes affectes
Les humains et autres mammifères