Cozaar
Categorie
Cozaar Les marques, Cozaar Analogs
Cozaar Les marques melange
Cozaar Formule chimique
C22H23ClN6O
Cozaar RX lien
http://www.rxlist.com/cgi/generic/losar.htm
Cozaar FDA fiche
Cozaar msds (fiche de securite des materiaux)
Cozaar Synthese de reference
DJ Carini et al., US. 5,138,69 (1992)
Cozaar Poids moleculaire
422.911 g/mol
Cozaar Point de fusion
183.5-184.5 oC
Cozaar H2O Solubilite
Cozaar Etat
Solid
Cozaar LogP
5.438
Cozaar Formes pharmaceutiques
Tablet
Cozaar Indication
Pour le traitement de l'hypertension.
Cozaar Pharmacologie
Le losartan est le premier d'une classe d'agents antihypertenseurs, l'angiotensine II (AG II) des antagonistes du récepteur. Il est, avec ses plus agissant métabolite actif (E-3174), une sélection spécifique et Antagoniste des récepteurs AT1. Le losartan bloque l'effet vasoconstricteur et de sécrétion d'aldostérone effets de l'angiotensine II en bloquant sélectivement la liaison de l'angiotensine II au récepteur AT1 trouve dans de nombreux tissus (par exemple, le muscle lisse vasculaire, glande surrénale).
Cozaar Absorption
Eh bien absorbée, la biodisponibilité systémique du losartan est d'environ 33%
Cozaar Toxicite
Hypotension et une tachycardie bradycardie peut survenir à partir parasympathique (vagal), DL50 = 1000 mg / kg (par voie orale chez le rat)
Cozaar Information pour les patients
PATIENT INFORMATION
Losartan potassium is used to treat high blood pressure. It may be used alone
or with other medications for high blood pressure. This medication should,
generally, not be used during pregnancy. If you are pregnant or considering
becoming pregnant, inform your physician immediately to discuss the risks
versus benefits. There are few side effects associated with losartan potassium.
Those most frequently reported, cough, upper respiratory infection and
dizziness, occurred no more frequently than in patients who did not take this
medication. You may take this medication with or without food. You should have
your blood pressure checked regularly
Losartan potassium is used to treat high blood pressure. It may be used alone
or with other medications for high blood pressure. This medication should,
generally, not be used during pregnancy. If you are pregnant or considering
becoming pregnant, inform your physician immediately to discuss the risks
versus benefits. There are few side effects associated with losartan potassium.
Those most frequently reported, cough, upper respiratory infection and
dizziness, occurred no more frequently than in patients who did not take this
medication. You may take this medication with or without food. You should have
your blood pressure checked regularly
Cozaar Organismes affectes
Les humains et autres mammifères
