Codimal
Categorie
Codimal Les marques, Codimal Analogs
Codimal Les marques melange
Codimal Formule chimique
C9H13NO
Codimal RX lien
No information avaliable
Codimal FDA fiche
Codimal msds (fiche de securite des materiaux)
Codimal Synthese de reference
Vanderbitle, Hass, Ind. Chem. 32, 34 (1940)
Codimal Poids moleculaire
151.206 g/mol
Codimal Point de fusion
190-194 oC
Codimal H2O Solubilite
Librement soluble
Codimal Etat
Solid
Codimal LogP
0.974
Codimal Formes pharmaceutiques
Tablet; Injection; Sirop
Codimal Indication
Pour le traitement de la congestion nasale, le contrôle de l'incontinence urinaire, priapisme et l'obésité.
Codimal Pharmacologie
Phénylpropanolamine (PPA), un agent sympathomimétique structurellement similaire à la pseudoéphédrine, est utilisé pour traiter la congestion nasale. Phénylpropanolamine se trouve dans les formulations de coupe-faim et avec guaifenesinin de toux froide formulations. En 2000, la FDA a demandé que toutes les compagnies pharmaceutiques arrêter la commercialisation de produits contenant de la phénylpropanolamine, due à une augmentation du risque d'AVC hémorragique chez les femmes qui ont utilisé la phénylpropanolamine.
Codimal Absorption
Biodisponibilité réduite (environ 38%) à partir du tractus gastro-intestinal, car le métabolisme de premier passage par la monoamine oxydase dans l'estomac et le foie.
Codimal Toxicite
Peut provoquer des extrasystoles ventriculaires et des paroxysmes court de tachycardie ventriculaire, une sensation de plénitude dans la tête et des fourmillements des extrémités; DL50 = 1490mg/kg (voie orale chez le rat)
Codimal Information pour les patients
PATIENT INFORMATION
Description
--------------------------------------------------------------------------------
This medicine is used to treat nasal congestion caused by colds or hay fever. Your doctor may prescribe this medicine for
other conditions as well.
General Information
--------------------------------------------------------------------------------
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in
this database. If you have questions about your medicines, talk to your healthcare provider.
Proper use of this medicine
--------------------------------------------------------------------------------
For proper use of this medicine, follow the directions on the package, unless otherwise instructed by your doctor. To use
a nose spray: gently blow your nose. Then sit back and tilt your head back slightly. Place the tip of the spray container
into the nose. Close off the other nostril with your other hand. Spray into the nose. Wait at least one minute in between
sprays. After using, rinse the tip of the sprayer in hot water and dry. This prevents contamination.
Missed Dose
--------------------------------------------------------------------------------
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your
regular schedule. Do not double doses.
Storage
--------------------------------------------------------------------------------
Follow package directions for proper storage. Keep away from heat, moisture or light.
Possible Side Effects
--------------------------------------------------------------------------------
Some common side effects reported with this medicine include:
stinging
burning
sneezing
increase in nasal discharge
If you experience other bothersome side effects, talk to your health care provider.
Some common side effects with this medicine include:
burning or stinging inside your nose
confusion
nervousness
headache
nausea
vomiting
Report any of the following to your doctor:
dizziness
or fainting spells
difficulty breathing
chest pain
rapid heart beat
increased sweating
tingling or numbness in the hands or feet
Warnings/Precautions
--------------------------------------------------------------------------------
Do NOT use more that the recommended dose of this medicine.
Do NOT use more of this medicine or longer than prescribed.
Using this medicine longer that 3-5 days can cause a condition known as "rebound congestion".
Overdose
--------------------------------------------------------------------------------
Seek medical attention immediately. For non emergencies, contact your local or regional poison control center
Drug Interactions
--------------------------------------------------------------------------------
This medicine can cause in increase in toxic effects to the heart when taken with other stimulants. Avoid taking with:
theophylline
digoxin
general anesthetics
atropine
MAO inhibitors.
Taking this medicine with the following herbs can cause increased side effects including high blood pressure and should be
avoided:
ephedra
yohimbe
This medicine can interact with the following drugs:
atropine
bromocriptine
diuretics (water pills)
linezolid
maprotiline
drugs used for depression
high blood pressure medications
drugs used for migraine headaches
oxytocin
vasopressin
For more information on specific drug interactions, talk to your doctor or pharmacist.
Pregnancy/Nursing
--------------------------------------------------------------------------------
Talk to your doctor about using this medicine during pregnancy or nursing to discuss any possible risks to you or your baby.
More Information
--------------------------------------------------------------------------------
For more information about this medicine, talk to your healthcare provider.
Description
--------------------------------------------------------------------------------
This medicine is used to treat nasal congestion caused by colds or hay fever. Your doctor may prescribe this medicine for
other conditions as well.
General Information
--------------------------------------------------------------------------------
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in
this database. If you have questions about your medicines, talk to your healthcare provider.
Proper use of this medicine
--------------------------------------------------------------------------------
For proper use of this medicine, follow the directions on the package, unless otherwise instructed by your doctor. To use
a nose spray: gently blow your nose. Then sit back and tilt your head back slightly. Place the tip of the spray container
into the nose. Close off the other nostril with your other hand. Spray into the nose. Wait at least one minute in between
sprays. After using, rinse the tip of the sprayer in hot water and dry. This prevents contamination.
Missed Dose
--------------------------------------------------------------------------------
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your
regular schedule. Do not double doses.
Storage
--------------------------------------------------------------------------------
Follow package directions for proper storage. Keep away from heat, moisture or light.
Possible Side Effects
--------------------------------------------------------------------------------
Some common side effects reported with this medicine include:
stinging
burning
sneezing
increase in nasal discharge
If you experience other bothersome side effects, talk to your health care provider.
Some common side effects with this medicine include:
burning or stinging inside your nose
confusion
nervousness
headache
nausea
vomiting
Report any of the following to your doctor:
dizziness
or fainting spells
difficulty breathing
chest pain
rapid heart beat
increased sweating
tingling or numbness in the hands or feet
Warnings/Precautions
--------------------------------------------------------------------------------
Do NOT use more that the recommended dose of this medicine.
Do NOT use more of this medicine or longer than prescribed.
Using this medicine longer that 3-5 days can cause a condition known as "rebound congestion".
Overdose
--------------------------------------------------------------------------------
Seek medical attention immediately. For non emergencies, contact your local or regional poison control center
Drug Interactions
--------------------------------------------------------------------------------
This medicine can cause in increase in toxic effects to the heart when taken with other stimulants. Avoid taking with:
theophylline
digoxin
general anesthetics
atropine
MAO inhibitors.
Taking this medicine with the following herbs can cause increased side effects including high blood pressure and should be
avoided:
ephedra
yohimbe
This medicine can interact with the following drugs:
atropine
bromocriptine
diuretics (water pills)
linezolid
maprotiline
drugs used for depression
high blood pressure medications
drugs used for migraine headaches
oxytocin
vasopressin
For more information on specific drug interactions, talk to your doctor or pharmacist.
Pregnancy/Nursing
--------------------------------------------------------------------------------
Talk to your doctor about using this medicine during pregnancy or nursing to discuss any possible risks to you or your baby.
More Information
--------------------------------------------------------------------------------
For more information about this medicine, talk to your healthcare provider.
Codimal Organismes affectes
Les humains et autres mammifères
