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Caryolysin Nombres de marca, Caryolysin Analogos

Caryolysin Marca los nombres de mezcla

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  • Caryolysin Formula quimica

    C5H11Cl2N

    Caryolysin RX enlace

    http://www.rxlist.com/cgi/generic3/mustargen.htm

    Caryolysin FDA hoja

    Caryolysin FDA

    Caryolysin MSDS (hoja de seguridad de materiales)

    Caryolysin MSDS

    Caryolysin Sintesis de referencia

    Hansen, los conocimientos tradicionales, et al;. J. Org;. 58, 6, 1359 a 1366 (1993)

    Caryolysin Peso molecular

    156.053 g/mol

    Caryolysin Punto de fusion

    108-111 oC

    Caryolysin H2O Solubilidad

    1.2E 004 mg / L

    Caryolysin Estado

    Solid

    Caryolysin LogP

    1.412

    Caryolysin Formas de dosificacion

    Viales de polvo para inyección, solución de la piel, ungüento

    Caryolysin Indicacion

    Para el tratamiento paliativo de la enfermedad de Hodgkin (estadios III y IV), linfosarcoma, leucemia linfocítica crónica mieloide o crónica, policitemia vera, la micosis fungoide y el carcinoma broncogénico. También para el tratamiento paliativo del carcinoma metastásico que resulta en el derrame.

    Caryolysin Farmacologia

    Mecloretamina también conocido como mustina, mostaza nitrogenada, y HN2, es el prototipo de quimioterapia medicamento contra el cáncer. Uso clínico exitoso de mecloretamina dio a luz en el campo de la quimioterapia contra el cáncer. El fármaco es un análogo de gas mostaza y se deriva de la investigación tóxicos guerra química. Pertenece al grupo de agentes alquilantes nitrógeno mostaza. Los agentes alquilantes trabajo por tres mecanismos diferentes todos los que logran el mismo resultado final - la interrupción de la función del ADN y muerte celular.

    Caryolysin Absorcion

    Absorbe parcialmente después de la administración intracavitaria, muy probablemente debido a la rápida desactivación por los fluidos corporales.

    Caryolysin Toxicidad

    Los síntomas de sobreexposición incluyen leucopenia, anemia, trombocitopenia y una diátesis hemorrágica con sangrado tardío puede desarrollar posteriores. La muerte puede seguir. La DL50 por vía intravenosa es de 2 mg / kg y 1,6 mg / kg en ratones y ratas, respectivamente.

    Caryolysin Informacion de Pacientes

    PATIENT INFORMATION

    NOTE: This information does not apply if mechlorethamine is applied to skin.
    Please see "For the patient: Mechlorethamine for skin".

    Mechlorethamine (meh-klor-ETH-ah-meen) is a drug that is used to treat some
    kinds of cancer. It is a clear liquid that is usually injected into a vein.
    A blood sample will be taken before each treatment. The dose and timing of
    your chemotherapy may be changed based on your blood counts and/or other side
    effects.
    Your doctor may tell you to drink lots of liquids (8-12 cups a day). This
    helps prevent kidney problems in some kinds of cancer.
    Other drugs may interact with mechlorethamine. Tell your doctor if you are
    taking any other drugs as your dose may need to be changed. Check with your
    doctor or pharmacist before you start taking any new drugs.
    The drinking of alcohol (in small amounts) will not affect the safety or
    usefulness of mechlorethamine.
    Mechlorethamine may cause sterility in men and menopause in women which may
    be permanent. If you plan to have children, discuss this with your doctor
    before being treated with mechlorethamine.
    Mechlorethamine may damage sperm and may harm the baby if used during pregnancy.
    It is best to use birth control while being treated with mechlorethamine. Tell
    your doctor right away if you or your partner becomes pregnant. Do not breast
    feed during treatment.
    Tell doctors or dentists that you are being treated with mechlorethamine before
    you receive any treatment from them.

    SEE YOUR DOCTOR OR GET EMERGENCY HELP IMMEDIATELY IF YOU HAVE:

    Signs of an infection such as fever (over 100F or 38C); chills; cough; sore
    throat; pain or burning when you pass urine; redness, pain or swelling of any
    area of your body; sores forming anywhere on your body.
    Signs of bleeding problems such as black, tarry stools; blood in urine; pinpoint
    red spots on skin.
    SEE YOUR DOCTOR AS SOON AS POSSIBLE (DURING OFFICE HOURS) IF YOU HAVE:

    Signs of kidney problems such as lower back or side pain, swelling of feet or
    lower legs, numbness or tingling in feet or hands.
    Signs of gout such as joint pain.
    CHECK WITH YOUR DOCTOR IF ANY OF THE FOLLOWING CONTINUE OR BOTHER YOU:

    Uncontrolled nausea, vomiting or diarrhea.
    Easy bruising or bleeding.
    Redness, swelling, pain or sores where the needle was placed.
    Redness, swelling, pain or sores on your lips, tongue, mouth or throat.
    Skin rash.
    NOTE: This information does not apply if mechlorethamine is applied to skin.
    Please see "For the patient: Mechlorethamine for skin".

    Mechlorethamine (meh-klor-ETH-ah-meen) is a drug that is used to treat some
    kinds of cancer. It is a clear liquid that is usually injected into a vein.
    A blood sample will be taken before each treatment. The dose and timing of
    your chemotherapy may be changed based on your blood counts and/or other
    side effects.
    Your doctor may tell you to drink lots of liquids (8-12 cups a day). This
    helps prevent kidney problems in some kinds of cancer.
    Other drugs may interact with mechlorethamine. Tell your doctor if you are
    taking any other drugs as your dose may need to be changed. Check with your
    doctor or pharmacist before you start taking any new drugs.
    The drinking of alcohol (in small amounts) will not affect the safety or
    usefulness of mechlorethamine.
    Mechlorethamine may cause sterility in men and menopause in women which may
    be permanent. If you plan to have children, discuss this with your doctor
    before being treated with mechlorethamine.
    Mechlorethamine may damage sperm and may harm the baby if used during pregnancy.
    It is best to use birth control while being treated with mechlorethamine. Tell
    your doctor right away if you or your partner becomes pregnant. Do not breast
    feed during treatment.
    Tell doctors or dentists that you are being treated with mechlorethamine before
    you receive any treatment from them.

    SEE YOUR DOCTOR OR GET EMERGENCY HELP IMMEDIATELY IF YOU HAVE:

    Signs of an infection such as fever (over 100F or 38C); chills; cough; sore
    throat; pain or burning when you pass urine; redness, pain or swelling of any
    area of your body; sores forming anywhere on your body.
    Signs of bleeding problems such as black, tarry stools; blood in urine; pinpoint
    red spots on skin.
    SEE YOUR DOCTOR AS SOON AS POSSIBLE (DURING OFFICE HOURS) IF YOU HAVE:

    Signs of kidney problems such as lower back or side pain, swelling of feet or
    lower legs, numbness or tingling in feet or hands.
    Signs of gout such as joint pain.
    CHECK WITH YOUR DOCTOR IF ANY OF THE FOLLOWING CONTINUE OR BOTHER YOU:

    Uncontrolled nausea, vomiting or diarrhea.
    Easy bruising or bleeding.
    Redness, swelling, pain or sores where the needle was placed.
    Redness, swelling, pain or sores on your lips, tongue, mouth or throat.
    Skin rash.

    Caryolysin Organismos afectados

    Humanos y otros mamíferos