antiVEGF
antiVEGF Brand names, antiVEGF Analogs
antiVEGF Brand Names Mixture
- No information avaliable
antiVEGF Chemical_Formula
No information avaliable
antiVEGF RX_link
http://www.rxlist.com/cgi/generic3/avastin.htm
antiVEGF fda sheet
antiVEGF msds (material safety sheet)
antiVEGF Synthesis Reference
sequence listed in Presta LG, Chen H, O'Connor SJ, et al Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res, 57: 4593-9, 1997
antiVEGF Molecular Weight
No information avaliable
antiVEGF Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
antiVEGF H2O Solubility
No information avaliable
antiVEGF State
Liquid
antiVEGF LogP
No information avaliable
antiVEGF Dosage Forms
Solution (IV Infusion)
antiVEGF Indication
For treatment of metastatic colorectal cancer
antiVEGF Pharmacology
Bevacizumab prevents or reduces the formation of blood vessels (angiogenesis) thereby preventing or reducing metatstatic disease progressing. Bevacizumab binds VEGF and prevents vascular endothelial growth and endothelial cell proliferation.
antiVEGF Absorption
No information avaliable
antiVEGF side effects and Toxicity
No information avaliable
antiVEGF Patient Information
No information avaliable
antiVEGF Organisms Affected
Humans and other mammals
