Avastin (Genentech Inc)
Avastin (Genentech Inc) Brand names, Avastin (Genentech Inc) Analogs
Avastin (Genentech Inc) Brand Names Mixture
- No information avaliable
Avastin (Genentech Inc) Chemical_Formula
No information avaliable
Avastin (Genentech Inc) RX_link
http://www.rxlist.com/cgi/generic3/avastin.htm
Avastin (Genentech Inc) fda sheet
Avastin (Genentech Inc) msds (material safety sheet)
Avastin (Genentech Inc) Synthesis Reference
sequence listed in Presta LG, Chen H, O'Connor SJ, et al Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res, 57: 4593-9, 1997
Avastin (Genentech Inc) Molecular Weight
No information avaliable
Avastin (Genentech Inc) Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Avastin (Genentech Inc) H2O Solubility
No information avaliable
Avastin (Genentech Inc) State
Liquid
Avastin (Genentech Inc) LogP
No information avaliable
Avastin (Genentech Inc) Dosage Forms
Solution (IV Infusion)
Avastin (Genentech Inc) Indication
For treatment of metastatic colorectal cancer
Avastin (Genentech Inc) Pharmacology
Bevacizumab prevents or reduces the formation of blood vessels (angiogenesis) thereby preventing or reducing metatstatic disease progressing. Bevacizumab binds VEGF and prevents vascular endothelial growth and endothelial cell proliferation.
Avastin (Genentech Inc) Absorption
No information avaliable
Avastin (Genentech Inc) side effects and Toxicity
No information avaliable
Avastin (Genentech Inc) Patient Information
No information avaliable
Avastin (Genentech Inc) Organisms Affected
Humans and other mammals
