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Vaprisol (TN) Brand names, Vaprisol (TN) Analogs

Vaprisol (TN) Brand Names Mixture

  • No information avaliable

Vaprisol (TN) Chemical_Formula


Vaprisol (TN) RX_link

Vaprisol (TN) fda sheet

Vaprisol_(TN) FDA

Vaprisol (TN) msds (material safety sheet)

Vaprisol (TN) Synthesis Reference

No information avaliable

Vaprisol (TN) Molecular Weight

585.649 g/mol

Vaprisol (TN) Melting Point

No information avaliable

Vaprisol (TN) H2O Solubility

No information avaliable

Vaprisol (TN) State


Vaprisol (TN) LogP


Vaprisol (TN) Dosage Forms

Injection (IV infusion, 50mg/vial)

Vaprisol (TN) Indication

For the treatment of infections caused by susceptible strains of the designated microorganisms in the following conditions: Complicated skin and skin structure infections caused by Escherichia coli, Enterococcus faecalis (vancomycin-susceptible isolates only), Staphylococcus aureus (methicillin-susceptible and -resistant isolates), Streptococcus agalactiae, Streptococcus anginosus grp. (includes S. anginosus, S. intermedius, and S. constellatus), Streptococcus pyogenes and Bacteroides fragilis. Complicated intra-abdominal infections caused by Citrobacter freundii, Enterobacter cloacae, Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae, Enterococcus faecalis (vancomycin-susceptible isolates only), Staphylococcus aureus (methicillin-susceptible isolates only), Streptococcus anginosus grp. (includes S. anginosus, S. intermedius, and S. constellatus), Bacteroides fragilis, Bacteroides thetaiotaomicron, Bacteroides uniformis, Bacteroides vulgatus, Clostridium perfringens, and Peptostreptococcus micros.

Vaprisol (TN) Pharmacology

Tigecycline is the first clinically-available drug in a new class of antibiotics called the glycylcyclines. Glycylcyclines are a new class of antibiotics derived from tetracycline. These tetracycline analogues are specifically designed to overcome two common mechanisms of tetracycline resistance, namely resistance mediated by acquired efflux pumps and/or ribosomal protection. Glycylcycline antibiotics have a similar mechanism of action as tetracycline antibiotics. Both classes of antibiotics bind to the 30S ribosomal subunit to prevent the amino-acyl tRNA from binding to the A site of the ribosome. However, the glycylcyclines appear to bind more effectively than the tetracyclines.

Vaprisol (TN) Absorption

No information avaliable

Vaprisol (TN) side effects and Toxicity

Since glycylcyclines are similar to tetracyclines, they share many of the same side effects and contraindications as tetracyclines. These side effects may include nausea/vomiting, headache, photosensitivity, discoloration of growing teeth, and fetal damage.

Vaprisol (TN) Patient Information

Vaprisol (TN) Organisms Affected

Enteric bacteria and other eubacteria