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Urokinase Brand names, Urokinase Analogs

Urokinase Brand Names Mixture

  • No information avaliable

Urokinase Chemical_Formula


Urokinase RX_link


Urokinase fda sheet


Urokinase msds (material safety sheet)

Urokinase Synthesis Reference

PMID 2987867

Urokinase Molecular Weight


Urokinase Melting Point

76 oC at pH 4.5 (Nowak, U.K. et al., Biochemistry 33:2951-2960 (1994).

Urokinase H2O Solubility

No information avaliable

Urokinase State


Urokinase LogP


Urokinase Dosage Forms

Powder for solution; Solution (IV infusion)

Urokinase Indication

For the treatment of pulminary embolism, coronary artery thrombosis and IV catheter clearance

Urokinase Pharmacology

Urokinase is used for the treatment of pulmonary embolisms. The low molecular weight form of human urokinase consists of an A chain of 2,000 daltons linked by a sulfhydryl bond to a B chain of 30,400 daltons. Urokinase is an enzyme (protein) produced by the kidney, and found in the urine. There are two forms of urokinase which differ in molecular weight but have similar clinical effects. Urokinase is the low molecular weight form. Urokinase acts on the endogenous fibrinolytic system. It converts plasminogen to the enzyme plasmin. Plasmin degrades fibrin clots as well as fibrinogen and some other plasma proteins.

Urokinase Absorption

No information avaliable

Urokinase side effects and Toxicity

No information avaliable

Urokinase Patient Information


Urokinase Organisms Affected

Humans and other mammals