Trovafloxacin mesylate
Brand names,
Trovafloxacin mesylate
Analogs
Trovafloxacin mesylate
Brand Names Mixture
Trovafloxacin mesylate
Chemical_Formula
C30H34O13
Trovafloxacin mesylate
RX_link
No information avaliable
Trovafloxacin mesylate
fda sheet
Trovafloxacin mesylate
msds (material safety sheet)
Trovafloxacin mesylate
Synthesis Reference
No information avaliable
Trovafloxacin mesylate
Molecular Weight
602.583 g/mol
Trovafloxacin mesylate
Melting Point
203.5 oC
Trovafloxacin mesylate
H2O Solubility
4100 mg/L
Trovafloxacin mesylate
State
Solid
Trovafloxacin mesylate
LogP
-2.229
Trovafloxacin mesylate
Dosage Forms
No information avaliable
Trovafloxacin mesylate
Indication
Used internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates.
Trovafloxacin mesylate
Pharmacology
Picrotoxin is a toxin obtained from the seeds of the shrub Anamirta cocculus. It is used as a central nervous system stimulant, antidote, convulsant, and GABA (gamma aminobutyric acid) antagonist. It is a noncompetitive antagonist at GABAA receptors and thus a convulsant. Picrotoxin blocks the GABAActivated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially barbiturates.
Trovafloxacin mesylate
Absorption
No information avaliable
Trovafloxacin mesylate
side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg. In large doses it is a powerful poison, causing unconsciousness, delirium, convulsions, gastro-enteritis and stimulation of the respiratory centre followed by paralysis, from which death sometimes results.
Trovafloxacin mesylate
Patient Information
No information avaliable
Trovafloxacin mesylate
Organisms Affected
Humans and other mammals